We read with interest the paper by Michiels et al on the prediction of cancer with microarrays and the commentary by Ioannidis listing the potential as well as the limitations of this approach (February 5, p 488 and 454). Cancer is a disease characterized by complex, heterogeneous mechanisms and studies to define factors that can direct new drug discovery and use should be encouraged. However, this is easier said than done. Casti teaches that a better understanding does not necessarily extrapolate to better prediction, and that useful prediction is possible without complete understanding (1). To attempt both, explanation and prediction, in a single nonmathematical construct, is a tall order (Figure 1).

The WW{gamma} triple gauge boson coupling parameters are studied using p{bar p} {yields} {ell}{nu}{gamma} + X({ell} = e, {mu}) events at {radical}s = 1.96 TeV. The data were collected with the D0 detector from an integrated luminosity of 162 pb{sup -1} delivered by the Fermilab Tevatron Collider. The cross section times branching fraction for p{bar p} {yields} W({gamma}) + X {yields} {ell}{nu}{gamma} + X with E{sub T}{sup {gamma}} > 8 GeV and {Delta}R{sub {ell}{gamma}} > 0.7 is 14.8 {+-} 1.6(stat) {+-} 1.0(syst) {+-} 1.0(lum) pb. The one-dimensional 95% confidence level limits on anomalous couplings are -0.88 < {Delta}{kappa}{sub {gamma}} < 0.96 and -0.20 < {lambda}{sub {gamma}} < 0.20.

Weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.

Weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.

Weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.

This document presents the results of groundwater and vadose zone monitoring for fiscal year 2004 (October 2003 through September 2004)on the U.S. Department of Energy's Hanford Site in southeast Washington State.

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We present a K{pi} mass spectrum analysis of the four-body semileptonic charm decay D{sup +} {yields} K{sup -}{pi}{sup +}{mu}{sup +}{nu} in the range of 0.65 GeV/c{sup 2} < m{sub K{pi}} < 1.5 GeV/c{sup 2}. We observe a non-resonant contribution of 5.30 {+-} 0.74{sub -0.51}{sup +0.99}% with respect to the total D{sup +} {yields} K{sup -} {pi}{sup +}{mu}{sup +}{nu} decay. For the K*(892){sup 0} resonance, we obtain a mass of 895.41 {+-} 0.32{sub -0.36}{sup +0.35} NeV/c{sup 2}, a width of 47.79 {+-} 0.86{sub -1.1}{sup +1.3} MeV/c{sup 2}, and a Blatt-Weisskopf damping factor parameter of 3.96 {+-} 0.54{sub -0.90}{sup +0.72} GeV{sup -1}. We also report 90% CL upper limits of 1.60% and 1.90% for the branching ratios {Lambda}(D{sup +} {yields} {bar K}*(1680){sup 0} {mu}{sup +}{nu})/{Lambda}(D{sup +} {yields} K{sup -} {pi}{sup +}{mu}{sup +}{nu}) and {Lambda}(D{sup +} {yields} {bar K}*{sub 0}(1430){sup 0}) {mu}{sup +}{nu}/{Lambda}(D{sup +} {yields} K{sup -}{pi}{sup +}) {mu}{sup +}{nu}, respectively.

The objective was to provide guidance for studies planning for the next five years. The workshop began with the premise that much has been accomplished during the last decade of MMS socioeconomic research and that it is time to assess future directions for the program. The workshop sought advice, rather than consensus, on key questions, useful analytical approaches, and critical information needs.

The report is providing current awareness in all aspects of offshore oil and gas development. Sixteen quarterly issues were prepared from January 2001 to October 2004 that contained approximately 2,250 citations.

Weekly newspaper from Port Aransas, Texas on Mustang Island that includes local, state and national news along with extensive advertising.

Weekly newspaper from Port Aransas, Texas on Mustang Island that includes local, state and national news along with extensive advertising.

Weekly newspaper from Port Aransas, Texas on Mustang Island that includes local, state and national news along with extensive advertising.

To date, all varistors used in ferroelectric neutron generators have been supplied from a single, proprietary source, General Electric Corporate Research and Development (GE CR&D). To protect against the vulnerability of a single source, Sandia initiated a program in the early 1980's to develop a second source for this material. A chemical preparation process for making homogeneous, high purity ZnO-based varistor powder was generated, scaled to production quantities, and transferred to external suppliers. In 1992, the chem-prep varistor program was suspended when it appeared there was sufficient inventory of GE CR&D material to supply ferroelectric neutron generator production for many years. In 1999, neutron generator production schedules increased substantially, resulting in a predicted exhaustion of the existing supply of varistor material within five years. The chem-prep program was restarted in January, 2000. The goals of the program were to (1) duplicate the chem-prep powder synthesis process that had been qualified for WR production, (2) demonstrate sintered billets from the chem-prep powder met requirements, (3) develop a process for rod fabrication and demonstrate that all component specifications could be met, and (4) optimize the process from powder synthesis through component fabrication for full-scale production. The first three of these goals have …

Semi-weekly newspaper from Livingston, Texas that includes local, state and national news along with advertising.

Semiweekly newspaper from Levelland, Texas that includes local, state, and national news along with advertising.

Weekly newspaper from Tulia, Texas that includes local, state and national news along with extensive advertising.

This report provides information regarding options available, their advantages and disadvantages, and the costs for pursuing activities to advance Smith River Rancheria toward an energy program that reduces their energy costs, allows greater self-sufficiency and stimulates economic development and employment opportunities within and around the reservation. The primary subjects addressed in this report are as follow: (1) Baseline Assessment of Current Energy Costs--An evaluation of the historical energy costs for Smith River was conducted to identify the costs for each component of their energy supply to better assess changes that can be considered for energy cost reductions. (2) Research Viable Energy Options--This includes a general description of many power generation technologies and identification of their relative costs, advantages and disadvantages. Through this research the generation technology options that are most suited for this application were identified. (3) Project Development Considerations--The basic steps and associated challenges of developing a generation project utilizing the selected technologies are identified and discussed. This included items like selling to third parties, wheeling, electrical interconnections, fuel supply, permitting, standby power, and transmission studies. (4) Energy Conservation--The myriad of federal, state and utility programs offered for low-income weatherization and utility bill payment assistance are identified, their qualification …

This report provides information regarding options available, their advantages and disadvantages, and the costs for pursuing activities to advance Smith River Rancheria toward an energy program that reduces their energy costs, allows greater self-sufficiency and stimulates economic development and employment opportunities within and around the reservation. The primary subjects addressed in this report are as follows: (1) Baseline Assessment of Current Energy Costs--An evaluation of the historical energy costs for Smith River was conducted to identify the costs for each component of their energy supply to better assess changes that can be considered for energy cost reductions. (2) Research Viable Energy Options--This includes a general description of many power generation technologies and identification of their relative costs, advantages and disadvantages. Through this research the generation technology options that are most suited for this application were identified. (3) Project Development Considerations--The basic steps and associated challenges of developing a generation project utilizing the selected technologies are identified and discussed. This included items like selling to third parties, wheeling, electrical interconnections, fuel supply, permitting, standby power, and transmission studies. (4) Energy Conservation--The myriad of federal, state and utility programs offered for low-income weatherization and utility bill payment assistance are identified, their qualification …

Semi-weekly newspaper from Livingston, Texas that includes local, state and national news along with advertising.

Weekly newspaper from Emory, Texas that includes local, state, and national news along with advertising.

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Monthly newspaper from Oklahoma City, Oklahoma that includes news and information about the Churches of Christ along with advertising.