This study evaluates archival data from a home intervention with an at-risk preschool child and her family. The intervention model studied was created by the Developmental Research Lab at Texas Christian University. Data was collected prior to and during the first 4 weeks of intervention to assess change in parent-child interaction, behavior and neurochemical profile. Measures used include coding of videotape recordings of the intervention, neurotransmitter levels taken via subject urine samples, Child Behavior Checklist, Parent Stress Index, and ACTeRS Parent Form. Results suggest positive change in parent-child interaction, behavior and neurochemical profile. However, consistent growth was not observed in several neurochemical results. Future studies should assess the entirety of the home intervention model and with a larger sample size.