MYB30 Orchestrates Systemic Reactive Oxygen Signaling and Plant Acclimation (open access)

MYB30 Orchestrates Systemic Reactive Oxygen Signaling and Plant Acclimation

This article explores the relationship among MYB30, the ROS wave, and systemic acclimation in Arabidopsis by determining the SAA response to HL stress of MYB30 mutants and wild-type plants.
Date: July 22, 2020
Creator: Fichman, Yosef; Zandalinas, Sara I.; Sengupta, Soham; Burks, David J.; Meyers, Ronald J., Jr.; Azad, Rajeev K. et al.
System: The UNT Digital Library
Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing (open access)

Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing

This article demonstrates that whole genome sequencing is an efficient approach for identification of causative genes underlying symbiotic nitrogen fixation defective phenotypes in Medicago truncatula Tnt1 insertion mutants obtained via forward genetic screens.
Date: February 27, 2016
Creator: Veerappan, Vijaykumar; Jani, Mehul; Kadel, Khem; Troiani, Taylor; Gale, Ronny; Mayes, Tyler et al.
System: The UNT Digital Library
ABA Is Required for Plant Acclimation to a Combination of Salt and Heat Stress (open access)

ABA Is Required for Plant Acclimation to a Combination of Salt and Heat Stress

This article highlights the important role abscisic acid plays in the acclimation of plants to a combination of two different abiotic stresses.
Date: January 29, 2016
Creator: Suzuki, Nobuhiro; Bassil, Elias; Hamilton, Jason S.; Inupakutika, Madhuri A.; Zandalinas, Sara I.; Tripathy, Deesha et al.
System: The UNT Digital Library
Gene-Level Analysis of Anthracycline-Induced Cardiomyopathy in Cancer Survivors (open access)

Gene-Level Analysis of Anthracycline-Induced Cardiomyopathy in Cancer Survivors

Article describes how anthracyclines are highly effective in treating cancer, despite increased risk of cardiomyopathy. This study examined gene-level associations with cardiomyopathy among cancer survivors using whole-exome sequencing data.
Date: September 12, 2023
Creator: Sharafeldin, Noha; Zhou, Liting; Singh, Purnima; Crossman, David K.; Wang, Xuexia; Hagerman, Lindsey et al.
System: The UNT Digital Library
Methods to evaluate rare variants gene-age interaction for triglycerides (open access)

Methods to evaluate rare variants gene-age interaction for triglycerides

This article discusses the development of two statistical methods to test the gene environment interaction effect of rare variants.
Date: September 17, 2018
Creator: Huayang Gao, Tony; Zhang, Jianjun; Medina Miguelangel, Diaz & Wang, Xuexia
System: The UNT Digital Library
Identification and characterization of a core set of ROS wave‐associated transcripts involved in the systemic acquired acclimation response of Arabidopsis to excess light (open access)

Identification and characterization of a core set of ROS wave‐associated transcripts involved in the systemic acquired acclimation response of Arabidopsis to excess light

Article reveal that the systemic transcriptomic response of plants to excess light stress is extensive in the context of systemic acquired acclimation and involves an early (2 min) and transient stage of transcript expression that includes thousands of genes.
Date: December 6, 2018
Creator: Zandalinas, Sara I.; Sengupta, Soham; Burks, David; Azad, Rajeev K. & Mittler, Ron
System: The UNT Digital Library
Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans (open access)

Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans

This article discusses how RNA-sequencing analysis was performed to assess how a glucose-supplemented diet and/or a hyl-2 mutation altered the transcriptome.
Date: August 5, 2016
Creator: Ladage, Mary L.; King, Skylar D.; Burks, David J.; Quan, Daniel L.; Garcia, Anastacia M.; Azad, Rajeev K. et al.
System: The UNT Digital Library
Methods and Results From the Genome-Wide Association Group at Genetic Analysis Workshop 20 (open access)

Methods and Results From the Genome-Wide Association Group at Genetic Analysis Workshop 20

This article summarizes the contributions from the Genome-wide Association Study group (GWAS group) of the GAW20. The GWAS group contributions focused on topics such as association tests, phenotype imputation, and application of empirical kinships. This summary article reports on promising statistical approaches and findings of the members of the GWAS group applied on real and simulated data which encompass the current topics of epigenetic and pharmacogenomics.
Date: September 17, 2018
Creator: Wang, Xuexia; Boekstegers, Felix & Brinster, Regina
System: The UNT Digital Library
Methods and results from the genome-wide association group at GAW20 (open access)

Methods and results from the genome-wide association group at GAW20

This article reports on promising statistical approaches and findings of the members of the Genome-wide Association Study group applied on real and simulated data which encompass the current topics of epigenetic and pharmacogenomics.
Date: September 17, 2018
Creator: Wang, Xuexia; Boekstegers, Felix & Brinster, Regina
System: The UNT Digital Library
TS: A powerful truncated test to detect novel disease associated genes using publicly available gWAS summary data (open access)

TS: A powerful truncated test to detect novel disease associated genes using publicly available gWAS summary data

This article proposes a new truncated statistic method (TS) by utilizing a truncated method to find the genes that have a true contribution to the genetic association. The proposed truncated statistic outperforms existing methods. It can be employed to detect novel traits associated genes using GWAS summary data.
Date: May 4, 2020
Creator: Zhang, Jianjun; Guo, Xuan; Gonzales, Samantha; Yang, Jingjing & Wang, Xuexia
System: The UNT Digital Library