Radioactive Drug Research, Final Summary Report, July 1949 to October 1959 (open access)

Radioactive Drug Research, Final Summary Report, July 1949 to October 1959

Applications of radioisotopes in the preparation of labeled drugs are reviewed. Among the applications described are the preparation of carbon-14- labeled cardiac glycosides, and the biosyinthesis of carbon-14-labeled digitoxin, morphine, colchicine, atropine, podophyllotoxin, and nicotine. The fate and metabolism of many of these drugs were traced. Radiochemical procedures were developed for the synthesis of pure compounds of pharmacological interest labeled with carbon-14, sulfur-35, and tritium. Investigations were made on the phenomena of drug penetration into the central nervous system. Publications during the period are listed. (C.H.)
Date: January 15, 1960
Creator: Geiling, E. M. K. (Eugene Maximilian Karl), 1891-1971 & Roth, Lloyd J. (Lloyd Joseph), 1911-
Object Type: Report
System: The UNT Digital Library
Effects of X-Irradiation on the Plasmas of Chickens as Revealed by Serological Analysis. Part I, Whole Plasma Comparisons. Part II, Alteration of Proteins of the Liver (a Preliminary Report). Part III, Autoantibody Formation (a Preliminary Report) (open access)

Effects of X-Irradiation on the Plasmas of Chickens as Revealed by Serological Analysis. Part I, Whole Plasma Comparisons. Part II, Alteration of Proteins of the Liver (a Preliminary Report). Part III, Autoantibody Formation (a Preliminary Report)

Irradiation of a living animal with X-rays induces alternation in the proteins of cells in which ionization events occur. Systematic end-products such as the proteins of plasma would, by changes in quality and quantity divulge modification of their synthetic pathways, or compensatory responses of the hematopoietic systems to stresses caused by irradiation in other organs. Serological identification of proteins, a sensitive means of biochemical characterizations was chosen to reveal variations in the proteins of the plasmas of chickens that had been exposed to large, but sub-lethal, doses of X-ray irradiation. Turbidimetric comparisons were made of precipitation tests involving reactions between antisera produced in rabbits against the sera of normal chickens, and pre-irradiation and post-irradiation samples of plasma from 15 chickens.
Date: 1955
Creator: Leone, Charles A.
Object Type: Report
System: The UNT Digital Library
Media for Air Cleaning and Air-Assay Purposes : Final Summary Report for Period Ending December 31, 1954 (open access)

Media for Air Cleaning and Air-Assay Purposes : Final Summary Report for Period Ending December 31, 1954

Work was completed on the high-temperature, high efficiency air filter. Technical assistance was given at a large-scale, privately financed run of an all-glass medium. Full-size filers have been produced in quantity and are offered by manufacturers; it is considered that commercial manufacture has been established. A survey was made of air sampling practices at 37 laboratories. Analysis of the survey results indicated that 22 different kinds of air-sampling filer media were in use among the laboratories questioned. We have recommended that air-assay practice be simplified by use of fewer media. A group of five media has been proposed as adequate for meeting all requirements. Laboratory work was done on the development of a high-efficiency, low-ash, all-purpose, air-assay paper. Two methods of approach were tried. In one an effort was made to produce cellulose fibrils in sufficient quantity and quality to act as the fine-fiber component of a filter. Only moderate success was attained. Better promise was shown by combining synthetic organic microfibers with cellulose fibers in a wet-formed sheet. No plant work was undertaken on this item.
Date: October 3, 1955
Creator: unknown
Object Type: Report
System: The UNT Digital Library
Biological Effects of Thermal Neutrons and the B10 (n,c) Li7 Reaction (open access)

Biological Effects of Thermal Neutrons and the B10 (n,c) Li7 Reaction

Boron-10 has a high thermal neutron capture cross section (3880 barns). Following neutron capture, the subsequent nuclear disintegration produces an alpha particle and a lithium-7 nucleus with the release of an average of 2.34 MeV for the particle irradiation, and in 93% of the reactions there is also the emission of an 0.48 MeV gamma ray: [equation not transcribed]. The kinetic energy is divided between the lithium-7 nucleus and the alpha particle giving the equal and opposite momentums with a range in tissue of about 8-14μ or approximately 1 cell diameter (1). This fact and the reported favorable partition of boron between tumor and the normal brain suggested a possible therapeutic usefulness which has been investigated clinically. The object of our study is to document the biological effects of the B10 (n,α) Li7 reaction on the brain of dogs injected with boron-10 30 minutes prior to irradiation with thermal neutrons. For this, we felt it desirable to estimate a dose for the boron-10 reaction which if exceeded, produces destruction of normal tissue. This dose could then be a reference dose to be utilized as a maximal limit for the irradiation of normal tissue. We have assured that the largest fluence …
Date: January 13, 1964
Creator: Archambeau, J. O.; Alcober, V; Calvo, W. & Brenneis, H.
Object Type: Report
System: The UNT Digital Library
Medical and Health Physics Quarterly Report: October, November, and December, 1952 (open access)

Medical and Health Physics Quarterly Report: October, November, and December, 1952

Report of progress on the metabolic properties of various materials, biological studies of radiation effects, health chemistry and physics.
Date: February 18, 1953
Creator: University of California Radiation Laboratory
Object Type: Report
System: The UNT Digital Library
Chemistry Division Quarterly Report: September, October, November, 1952 (open access)

Chemistry Division Quarterly Report: September, October, November, 1952

Quarterly progress report for the Chemistry Division of the University of California Radiation Laboratory: nuclear chemistry, bio-organic chemistry, metals and high temperature thermodynamics, basic chemistry, and chemical engineering.
Date: December 31, 1952
Creator: University of California Radiation Laboratory
Object Type: Report
System: The UNT Digital Library
Ths Significance Of Beryllium Surface Contamination To Health (open access)

Ths Significance Of Beryllium Surface Contamination To Health

Surface contamination with beryllium becomes a hazard to health only when the potential exists for resuspension in air in enough quantity and for enough time to exceed the prescribed standards for airborne exposures. There are several factors governing the rate and nature of resuspension phenomena. These factors include: the quantity and properties of the particular beryllium compound causing the contamination, the nature of the surface, activities in the vicinity, ventilation in the area which might affect the dilution of resuspended particles, and the presence of other control measures such as respiratory protection and use of wet methods. Generally, it has been found that the problem is minimal and can be easily controlled by exercising good judgement based upon consideration of pertinent factors governing resuspension, and a knowledge of the nature of beryllium toxicity.
Date: May 27, 1964
Creator: Cohen, Jerry J. & Kusian, Ross N.
Object Type: Report
System: The UNT Digital Library
The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes (open access)

The Effects of 250-kv X-Ray on the Dog's Pancreas: Morphological and Functional Changes

Previous investigations that the pancreas is a radioresistant organ. Ivy in 1924 noted the presence of a fibrotic atrophic pancreas in a dog which had received one erythema dose to the epigastrium. Fisher in 1923 reported that four to five erythema doses delivered in a single application caused complete disappearance of the irradiated pancreatic remnant in about two months. These dogs died because of uncontrolled diabetes. One dog that received four erythema doses (possibly 200 r) was sacrificed after five months. At autopsy the irradiated pancreas had disappeared, but 275 mgm of regenerated pancreas were found at the base of the main duct and 100 mgm at the base of the accessory duct. Leven in 1933 implanted radon seeds into the pancreas. Dosages varied from 528 to 1584 millicurie hours. At postmorten the pancreas surrounding the seeds demonstrated fibrous atropy and foci of necrosis. The islets appeared normal but were relatively larger in size. Rauch in 1952 reported that dogs given 200 r in air over the pancreas on alternate days until a total of 1600 r was received failed to show any histological changes after two months. Lushbaugh and Spalding and Lushbaugh reported that over 1500 r of whole-body …
Date: February 1, 1963
Creator: Archamefau, John; Griem, Melvin & Harper, Paul
Object Type: Report
System: The UNT Digital Library
The Status of Meteorological Knowledge as a Factor in Air Pollution Control (open access)

The Status of Meteorological Knowledge as a Factor in Air Pollution Control

The first national Technical Conference on Air Pollution (1) held in this city in 1950 included eight papers on meteorology; the present session contains one. On this basis, one night conclude that recent progress in meteorology has been virtually nonexistent or that the importance of meteorological factors has been diminishing, Neither could be further from the truth, as the number and quality of papers relating to air pollution meteorology in recent scientific and technical sessions will attest. It is particularly appropriate to review the status of meteorological "know-how" at this time, because of the many situations in which the ultimate capability of the atmosphere to absorb pollution is in question. Both in connection with highly toxic materials on the one hand and the "megalopolis" on the other, estimates of the "atmospheric sewer capacity" are becoming increasingly necessary to industrial and municipal planning.
Date: 1968
Creator: Smith, Maynard E.
Object Type: Report
System: The UNT Digital Library
Hazardous Materials - Redox Plant (open access)

Hazardous Materials - Redox Plant

The Redox process uses or produces only a very few materials that are hazardous for reasons other than radioactivity. The conditions under which these materials become hazardous were carefully taken into consideration in the development of the process and design of the equipment. A considerable about of information on the hazardous properties of the process materials was obtained so that the pertinent material could be incorporated into the process specifications. Providing the equipment is operating properly and the process is being carried out within specification limits, no hazardous conditions can be created by the process. The purpose of this report is to assemble in a single, readily available document all of the information on the normal concentration limits and safe handling procedures needed to adequately control the use and storage of these materials. This report should be helpful in preparing safety bulletins and provide guidance in case of unusual incidents, malfunctioning of equipment, or contemplated changes in either the process or equipment. It is important to remember that a maximum allowable concentration (MAC) is only a limit on the concentration of a toxic material which cannot be exceeded in the air to which workers are constantly exposed to every working …
Date: May 22, 1956
Creator: Underwood, J. W.
Object Type: Report
System: The UNT Digital Library
Respiratory Protective Equipment, Progress Report for June 1959 to April 1960 (open access)

Respiratory Protective Equipment, Progress Report for June 1959 to April 1960

"Dust and gas masks and respirators have been an effective method under certain environmental conditions to reduce the inhalation of toxic aerosols. Under many conditions, however, their efficacy has been seriously questioned. It is the purpose of this study to evaluation over-all respirator performance on fine aerosols and to develop equipment whereby a greater degree of respiratory protection may be assured with reliability for highly toxic atmospheres."
Date: June 27, 1960
Creator: Silverman, Leslie; Fitzgerald, J. J., (Joseph James), 1919-; Burgess, William A.,1924-; Corn, Morton & Stein, Felix
Object Type: Report
System: The UNT Digital Library
Bibliography of Published Papers of the Atomic Bomb Casualty Commission (1947-1959) (open access)

Bibliography of Published Papers of the Atomic Bomb Casualty Commission (1947-1959)

References to 193 publications of staff members of the Atomic Bomb Casualty Commission during 1947 through 1959 are listed in both English and Japanese. Author and subject indexes are included.
Date: 1959
Creator: Atomic Bomb Casualty Commission
Object Type: Report
System: The UNT Digital Library
Biology Division Semi-Annual Progress Report for Period Ending February 15, 1964 (open access)

Biology Division Semi-Annual Progress Report for Period Ending February 15, 1964

Technical report on the activities of the Oak Ridge National Laboratory Biology Division for the report period including a list of 346 publication and lectures and 205 short articles by members of the division on their research and activities.
Date: May 1964
Creator: Hollaender, Alexander, 1898-1986 & Carson, Stanley F.
Object Type: Report
System: The UNT Digital Library

[INSITE Data Category: Project Construction Effects PC001-PC069]

Information collected from the United States Nuclear Regulatory Commission (USNRC) using the Information on Nuclear SITEs (INSITE) Information System. This document describes data for land use impacts, water use impacts, impacts on terrestrial ecological systems, impacts on aquatic ecological systems, social and economic impacts, and transmission line impacts.
Date: April 1978
Creator: U.S. Nuclear Regulatory Commission. Site Designation Standards Branch.
Object Type: Dataset
System: The UNT Digital Library

Scientific Computing Division FY-81 Cyber Rates and NOS/BE Scheduler Modifications

The following data is a code listing and sample case output calculating the steady state thermal-mechanical behavior of oxide fuel rods.
Date: January 1981
Creator: unknown
Object Type: Dataset
System: The UNT Digital Library
An Ecological Characterization of Coastal Maine (North and East of Cape Elizabeth): Volume 4. Appendices (open access)

An Ecological Characterization of Coastal Maine (North and East of Cape Elizabeth): Volume 4. Appendices

The appendices of a report regarding an ecological characterization of coastal Maine, North and East of Cape Elizabeth
Date: October 1980
Creator: Fefer, Stewart I. & Schettig, Patricia A.
Object Type: Report
System: The UNT Digital Library
Lower Mississippi Valley Ecological Inventory: User's Guide and Information Base (open access)

Lower Mississippi Valley Ecological Inventory: User's Guide and Information Base

"The objective [of this report] is to produce an inventory of those important ecological along the lower Mississippi River on which siting of major industrial facilities and land clearing operations could have an impact."
Date: May 1983
Creator: Beccasio, Angelo D.
Object Type: Report
System: The UNT Digital Library
An Ecological Characterization of Coastal Maine (North and East of Cape Elizabeth): Volume 5. Data Source Appendix (open access)

An Ecological Characterization of Coastal Maine (North and East of Cape Elizabeth): Volume 5. Data Source Appendix

The Data Source Appendix of a report regarding an ecological characterization of coastal Maine, North, and East of Cape Elizabeth
Date: October 1980
Creator: Fefer, Stewart I. & Schettig, Patricia A.
Object Type: Report
System: The UNT Digital Library
Tampa Bay Environmental Atlas (open access)

Tampa Bay Environmental Atlas

"The purpose of the Tampa Bay Environmental Atlas is to compile existing biological and water resource data for the Tampa Bay ecosystem and map these data at a scale of 1:24,000." (from Preface)
Date: December 1984
Creator: Kunneke, J. Thomas & Palik, Thomas F.
Object Type: Report
System: The UNT Digital Library
An Ecological Characterization of Coastal Maine (North and East of Cape Elizabeth): Volume 6. Atlas (open access)

An Ecological Characterization of Coastal Maine (North and East of Cape Elizabeth): Volume 6. Atlas

The Atlas of a report regarding an ecological characterization of coastal Maine, North and East of Cape Elizabeth.
Date: October 1980
Creator: Fefer, Stewart I. & Schettig, Patricia A.
Object Type: Report
System: The UNT Digital Library
Northwestern Florida Ecological Characterization: An Ecological Atlas. Map Narratives (open access)

Northwestern Florida Ecological Characterization: An Ecological Atlas. Map Narratives

A report regarding the Northwestern Florida Ecological Characterization study, the purpose of which is to compile existing information about the biological, social, and physical sciences for the gulf coastal counties of Florida from Escambia County to Hernando County.
Date: September 1984
Creator: Palik, Thomas F. & Kunneke, J. Thomas
Object Type: Report
System: The UNT Digital Library
Southwestern Florida Ecological Characterization: An Ecological Atlas. Map Narratives (open access)

Southwestern Florida Ecological Characterization: An Ecological Atlas. Map Narratives

A report regarding the Southwest Florida Ecological Characterization study, with the purpose of which is to compile existing information about the biological, social and physical sciences for the Gulf coastal counties of Florida from Pasco County to Monroe County, including the Florida Keys and Dry Tortugas.
Date: April 1984
Creator: Martel Laboratories
Object Type: Report
System: The UNT Digital Library
National Uranium Resource Evaluation, Ashland Quadrangle, Wisconsin, Michigan and Minnesota (open access)

National Uranium Resource Evaluation, Ashland Quadrangle, Wisconsin, Michigan and Minnesota

A report regarding evaluations done of the Ashland Quadrangle to find favorability for uranium occurrences in the quadrangles geologic environments. "No favorable areas could be identified or delineated on the basis of available data, and it is concluded that geologic environments in the Ashland Quadrangle are unfavorable for uranium."
Date: July 1982
Creator: Routledge, R. W.; Parrish, I. S. & Leigh, O. E.
Object Type: Report
System: The UNT Digital Library
Status of Uranium Exploration in Turkey (open access)

Status of Uranium Exploration in Turkey

Field evaluations made of uranium deposits located in and near southwestern Turkey
Date: October 1961
Creator: Kratchman, Jack
Object Type: Report
System: The UNT Digital Library