This Special Report assesses how Federal scientific and technical information (STI) can contribute to a more competitive America and what actions are needed to realize this potential. The report was prepared in response to a request from the House Committee on Science, Space, and Technology.

This Report, the first of the neuroscience series, discusses the risks posed by neurotoxic substances—substances that can adversely affect the nervous system—and evaluates the Federal research and regulatory programs now in place to address these risks.

This special report, the second of our neuroscience series, discusses the field of neural grafting into the brain and spinal cord to treat neurological disorders. It describes the technology of neural grafting, the neurological conditions that it may be used to treat, and the patient populations that are affected. Also, the legal and ethical issues raised by the development of neural grafting techniques are discussed. The report includes a range of options for congressional action related to the Federal funding of transplantation research using human fetal tissue, the adequacy of existing Federal laws and regulations regarding the use of human fetal tissue, and the role of the Federal Government in guiding the development and promoting the safety and efficacy of neural grafting procedures.

This background paper examines the epidemiologic evidence used by the CDC in deciding to revise the AIDS case definition and the impact the proposed definition will have on surveillance. The paper also explores the logistical consequences and other implications of the revised definition, including its impact on Social Security disability determinations.

This report describes the issues associated with genetic monitoring and screening in the workplace. It examines the technologies used, analyzes the legal framework for the use of such tests, assesses the ethical issues inherent in the use of these tools in the workplace setting, describes how genetic information is conveyed by a genetic counselor, and, based on an OTA survey of 1,500 U.S. companies and the largest unions, evaluates the current and future use of genetic monitoring and screening in the workplace.

This report reviews the mental health needs of Indian adolescents (those of American Indian and Alaska Native descent) and the services available to them. It summarizes the findings of the review, suggests options that Congress might consider, and provides an overview of other special health needs of adolescents (ages 10 to 18).

This report discusses the definition of honesty and integrity tests defined by OTA. The definition does not necessarily resolve ambiguities over the universe of tests that should be considered integrity tests. Controversy surrounds the meanings of integrity and honesty in the workplace; there is disagreement over whether integrity tests differ from other personnel tests in design or in the kinds of inferences they support; and there is little relative information on how integrity and honesty tests are actually used in hiring decisions.

This quarterly report includes formal assessments, technical memoranda, background papers, testimony, staff papers, and administrative documents for the Technology Assessment Board.

This report describes the unconventional cancer treatments that are most used by U.S. cancer patients; it describes the way in which people find out about them and how much they pay for them; reviews the claims made for them and the information base in support of the claims; suggests possible ways of generating valid information about their safety and effectiveness; and presents the legal issues surrounding unconventional treatments that have brought civil and criminal litigation to bear on the subject.

A report on High Definition Television (HDTV. During 1989, HDTV moved from obscurity to center stage in the ongoing debate over the role of the Federal Government in U.S. industrial competitiveness. HDTV and related High-Resolution System (HRS) technologies in the computer and communications sectors may significantly impact U.S. electronics manufacturing, accelerate fundamental restructuring of the U.S. communications infrastructure, and provide a host of valuable services.

This OTA report analyzes the problem of locating and arranging services for people with dementia, presents a framework for an effective system to connect them to appropriate services, and discusses congressional policy options for establishing such a system. One of the main policy issues is whether the system should serve people with dementia exclusively or serve people with other diseases and conditions as well.

This Background Paper examines the evidence of the effectiveness of drug abuse treatment; it also evaluates the role that such treatment might play in reducing the spread of HIV. Because most intravenous drug users are not in treatment, the paper also examines other approaches to HIV prevention among this high-risk group.

This report discusses the agricultural practices that are contributing to the contamination of groundwater, how to develop alternative practices, it outlines major components of the water quality issues, and describes the integrating and coordinating activities of the respective federal agencies.

The U.S. communication infrastructure is changing rapidly as a result of technological advances, deregulation, and an economic climate that is increasingly competitive. This change is affecting the way in which information is created, processed, transmitted, and provided to individuals and institutions. The report analyzes the implications of new communication technologies for business, politics, culture, and individuals, and suggests possible strategies and options for congressional consideration.