The distinction of positive and negative symptoms in schizophrenia was examined in relation to demographic, clinical and neuropsychological measures.

Research has consistently shown schizophrenics to perform significantly poorer than normal controls on commonly used measures of neuropsychological functioning. Research on the neuropsychological functioning of first-degree relatives of schizophrenics who do not themselves have schizophrenia is comparatively sparse but suggests the likelihood of deficits in this group as well. A battery of standard neuropsychological tests was administered to three groups: first-degree relatives of schizophrenics who do not themselves have schizophrenia (FDR-SCZ), first-degree relatives of persons with major depression and bipolar disorder (FDR-MOOD), and normal controls (NC). The FDRSCZ group was not found to demonstrate significantly impaired performance relative to the other two groups on any of the hypothesized or exploratory analyses. These implications of these findings are discussed with reference to previous studies and future research.

The clinical utility of the Intermediate Category Test, a measure of executive functioning in children 9 to 14 years of age, is currently limited by the availability of only a Total Error score for normative interpretation. The Process Scoring System (PSS) was developed to provide a standardized method of assessing specific processing patterns and problem-solving errors. The purpose of this study was to determine the ability of the PSS scores to discriminate between children with and without suspected executive deficits, thereby providing evidence of criterion-related validity.

The current study discussed the development and validation of the Checklist for Differential Diagnosis of Attentional Problems (CDDAP), a tool for use with adults seeking diagnosis and treatment of an Attention Deficit Hyperactivity Disorder. Normative data are provided on three subject groups (ADHD adults, controls, and adults with other psychiatric disorders). Convergent validity was established with the SCL-90, and criterion validity established through comparing scaled scores with final diagnoses. Overall, this measure was accurate at differentiating adults with ADHD from controls and adults with other psychiatric disorders. Results indicated that the CDDAP was also able to identify other psychiatric disorders with 71 to 92% accuracy, depending on the disorder.

Reitan and Wolfson's General Neuropsychological Deficit Scale and Left and Right Neuropsychological Deficit Scales were applied to Halstead-Reitan test data of individuals with psychotic or substance abuse disorders with and without a head injury.

The present study set out to investigate the biopsychosocial model of illness using variables previously identified as directly impacting illness or as mediating the relationship between other variables and illness. Oral contraceptive use, stress, and negative affect were investigated as predictors of immunological competence, measured by the level of Immunoglobulin G antibodies to Epstein-Barr Virus Viral Capsid Antigen (EBV-VCA IgG).

Recent literature suggests that not only does Attention-deficit Hyperactivity Disorder (ADHD/ADD) persist into adulthood, but it can also be accompanied by personality characteristics which cause emotional difficulties. In fact, adults diagnosed with ADHD can present with a profusion of difficulties. Several constructs appear to accumulate dynamically throughout development to place the adult with ADHD at risk for multiple emotional problems. These interwoven influences include familial characteristics, childhood emotional and academic difficulties, and inadequate coping skills to respond to adulthood pressures. This document, first, describes a developmental model for conceptualizing negative trajectories leading to nonadaptive coping and psychopathology and identifies personality factors of adults diagnosed with ADHD. This model provides clinicians and researchers with a better understanding of the complexity and challenges of adulthood ADHD in order to aid in diagnosis, treatment, and prevention. The purpose of this study is to examine personality factors common to adults diagnosed with ADHD and compares these characteristics with a group of adults diagnosed with a depressive disorder. Adults responding to a community advertisement who provided documentation of the diagnosis of Attention-deficit Hyperactivity Disorder were administered the MMPI-2. This ADHD group was compared with MMPI-2 profiles of a group of adults diagnosed with Major Depressive …

This study investigated the relationship between stress and pain crisis incidence in pediatric Sickle Cell Anemia (SCA). It was hypothesized that SCA children were exposed to higher levels of stress than healthy children. It was also hypothesized that a significant positive correlation existed between level of stress and pain crisis incidence both within and between years. The sample consisted of 20 Black elementary school children with SCA. There were 12 female and 8 male children. The period of investigation included the calendar years 1983 and 1984. Pain crisis incidence was determined through parent interviews and verified by a review of medical records.

The potential for human exposure to pesticides exists particularly for agricultural workers (i.e. migrant workers) and individuals within close proximity to pesticide-sprayed crops (i.e. those living on or near agricultural farms). Children, through biology and behavior, may be more susceptible and vulnerable to exposure to pesticides than adults. The purpose of this study was to examine young populations particularly at-risk for occupational or accidental exposure to pesticides and determine associated behavioral, emotional, and physical symptoms. A total of 444 students from two South Texas school districts completed questionnaires assessing level of risk of exposure to pesticides and were categorized into at-risk and low risk categories. Physical, emotional, and behavioral symptoms were obtained using the Youth Self-Report. Children who were at-risk demonstrated significantly higher scores on the Youth Self-Report (YSR) in the areas of anxious/depressed, attention problems, social problems, somatic complaints, thought problems, withdrawal, internalizing behaviors, and total problem behaviors than children who were at lower risk of pesticide exposure. Odds ratios were obtained and suggested that children in the at-risk category were more five times more likely to score in the clinically significant range on the Attention Problems subscale, and three times more likely to score in the clinically significant …

The objective of the present study was to evaluate the relationship between a set of cofactors and severity of cognitive impairment, to determine if there were any factors which significantly predicted more severe neurocognitive deficits in persons with AIDS. Twenty-four male volunteers recruited from community groups and physician referrals participated. Subjects completed several self-report questionnaires eliciting information regarding demographics and risk factor variables, in addition to a comprehensive battery of neuropsychological tests. A severity of cognitive impairment summary score was computed for each subject, reflecting both the number of impaired tests and their distance in the impaired direction from normative data. Neither CD4 count, number of months since diagnosis of AIDS, number of AIDS-related illnesses, number of recent stressors, history of head injury/LOC, history of substance use, current or past psychiatric disorder, history of learning disability nor history of other medical illness were found to be significantly related to severity of cognitive impairment in this sample, after controlling for the effects of age, level of education, estimated premorbid IQ and mood status. However, no reliable conclusions could be drawn from this study because the small sample size resulted in an unacceptably low level of statistical power for the desired regression …

Eighty-eight (N = 88) non-brain-injured adults were tested with one of two versions of the Booklet Category Test (BCT). Forty-four (N = 44) individuals were tested with the standard version of the BCT, and forty-four (N = 44) were tested with a revised BCT in which between-subtest cueing was removed, called the Noncued Category Test (NCT). The results of this study indicate that removal of cueing instructions changes the Category test significantly. Subjects administered the NCT scored significantly more errors than those who were administered the standard Category test. While BCT scores correlated significantly with nonverbal intelligence scores, NCT scores did not. However, the difference in these correlations was not significant, indicating that the intelligence aspect measured in the two versions is not different. Neither the BCT nor the NCT correlated significantly with the Wisconsin Card Sort, Word Fluency, Stroop, or Trail Making Test. It is recommended that the NCT be administered to circumscribed clinical populations in order to best utilize present findings.

Clinical depression is characterized by alterations in thoughts, judgment, cognition and social behavior. This study focuses on non-optimal views of self and significant others that are proposed to underlie many of these alterations. Perceptions of self and significant others were elicited using the Role Construct Repertory Grid (Kelly, 1955a). Participants included depressed outpatients with high levels of trait anxiety (n = 27), depressed outpatients with lower levels of trait anxiety (n = 29) and a control group of never-depressed volunteers (n = 28). Consistent with prediction, significant group differences were found for negative self perception, discrepancies between actual self and self goals, alienation from significant others, and inconsistencies in self image. Results provided partial support for the self discrepancy theory of emotionality (Higgins, 1987). Among depressed patients, higher levels of anxiety were associated with increased self negativity and greater discrepancies between actual self and self goals. Increased levels of depression were associated with more alienation from significant others and more consistency in self image. Depressed patients' judgments of self and others were altered from optimal ratios, as predicted by the theory of interpersonal judgment (LeFebvre, LeFebvre & Adams-Webber, 1986). Findings have theoretical and clinical importance for the understanding and treatment …

Psychopathic criminals commit more crimes, are more prone to recidivism, and more likely to engage in violent crimes and other aggressive behavior than nonpsychopathic criminals. Less is known about forensic patients, both with and without psychopathy, and their aggression. In the current study, patients in a maximum security hospital were examined with respect to their psychopathy and its predictive value on institutional management and dangerousness. In this regard, the Psychopathy Checklist (PCL) and the Psychopathy Checklist - Revised (PCL-R) have proven to be valid and reliable measures of psychopathy. The present study was an attempt to establish predictive validity for a new version: the Psychopathy Checklist Screening Version (PCLSV). As such, this study examined the PCL-SV's relationship to (a) diagnoses of Antisocial Personality Disorder according to DSM-III-R criteria and (b) the Personality Assessment Inventory (PAI) Aggression, Drug Problems, and Antisocial Features scales. The influence of major Axis I disorders on the assessment of psychopathy with the PCLSV was also examined. Participants were 150 male forensic psychiatric patients at Vernon State Hospital who were committed for various reasons: incompetence to stand trial, initial evaluation and treatment after having been found not guilty by reason of insanity, and manifest dangerousness. Chart reviews …

Numerous investigations with college students have found that mild depressives perceive environmental contingencies more accurately than do nondepressives. The present study explores this 'depressive realism' phenomenon in a hospitalized sample.

Recently, researchers have begun to explore the associated impacts of ADHD on parent and family functioning, with an increasing focus on parenting stress. Accumulating empirical evidence is mixed, suggesting that parents of children with ADHD report increased levels of parenting stress when compared to parents of children with learning disabilities, and parents of non-referred children, but report equally stressful parenting levels when compared to parents of children with externalizing behavior problems. Results of the present study comparing reported parenting stress levels between parents of children with ADHD, children with internalizing behavior problems, and nonreferred children, were partially supportive of results found in past studies indicating higher levels of parenting stress among parents of children with ADHD. However, strong gender effects were found between mothers and fathers, which mediated the overall results.

Children who have received radiation therapy for the treatment of brain tumors have been shown to experience neurocognitive deficits which appear to increase over time. The purpose of this study was to examine the memory functioning of 22 children irradiated for brain tumor and 22 healthy children of the same age who had not received irradiation. Subjects were administered a brief form of the WISC-III, to obtain an IQ, and the Wide Range Assessment of Memory and Learning (WRAML), to evaluate visual and verbal memory. Results indicated that, although there were no significant differences between the IQ scores of healthy children and children who had been irradiated, children who have received radiation therapy for brain tumor evidence memory deficits which effect visual and verbal memory abilities. Among the children who had been irradiated, as time since treatment increased, visual memory and overall memory functioning appeared to decline. Findings also suggested that children who received total tumor resection may evidence greater memory deficits than those who received only a partial resection. Visual memory was more closely related to IQ in the children irradiated for brain tumor than in the healthy children. The overall importance of research with this population lies in …

This study investigated the effect of cognitive factors on competency to stand trial. Previous researchers have investigated how psychological variables --such as psychosis and intelligence--contribute to incompetency. Although several researchers have established that intelligence contributes to incompetency, very few have investigated the role of specific cognitive abilities within the realm of intelligence. This study investigated the performance of 55 defendants referred for competency restoration on neuropsychological measures. Specifically, competent defendants and incompetent defendants were compared on several measures assessing functioning in seven cognitive domains. Competent defendants performed significantly better than incompetent defendants on measures of verbal comprehension, social judgment, verbal memory, and executive functioning. Competent and incompetent defendants did not differ on attention, visual spatial skills, or nonverbal memory.

The purpose of the present study was to assess patient improvement in a specific freestanding partial hospital. Improvement was assessed in two specific areas: 1) symptom reduction as measured by the Symptom Check List-90-Revised (SCL-90-R) and 2) social adjustment as measured by the Social Adjustment Scale Self-Report (SAS-SR) at admission, discharge and three month follow-up. In addition, improvement was assessed from two perspectives: 1) patient evaluation and 2) therapist evaluation. Results indicated that there was statistically significant improvement from admission to discharge on the SCL-90-R and the SAS-SR. This improvement was maintained from discharge to three month follow-up. Findings also revealed statistically significant improvement when analyzed from both the patient perspective and the therapist perspective.

Parents of children with Attention Deficit Hyperactivity Disorder (ADHD) are often reported as experiencing more stress than parents of normal children. The bulk of this research has been conducted primarily on a Caucasian population, however, providing little information regarding multicultural aspects of parenting stress. Research has also been lacking in attention given to the stress related to parenting a child with internalizing disorders. The purpose of this study was 1) to compare parenting stress reported by mothers of children with ADHD to parenting stress reported by mothers of children with depressive disorders, and 2) to compare parenting stress as reported by Caucasian, African American, and Hispanic mothers. Results indicated that mothers of ADHD children experienced more parenting stress related only to their children's hyperactive and distracting behaviors. Contrary to previous research, Caucasian mothers reported significantly more overall and parent-related parenting stress than African American mothers.

Performance on the Spatial Span subtest of the Wechsler Memory Scale has been viewed as an indicator of working memory and visuospatial processing. A number of factors including age and gender have been posited to effect performance on Spatial Span by older adults. The current study examined the impact of various forms of cognitive impairment and severity of impairment on Spatial Span performance. Five hundred thirty-eight individuals between the ages of 65 and 89 were evaluated in a university memory disorders clinic using a battery of neuropsychological tests that included Spatial Span. Participants were grouped by consensus diagnosis into type of cognitive impairment (Alzheimer's disease, vascular disease, amnestic mild cognitive impairment or non-amnestic mild cognitive impairment) or cognitively normal. As expected, an increase in severity of impairment results in a decrease in Spatial Span Total Score. Other findings included a weak relationship between age and Spatial Span Total Score. Gender, as well as age, did not fully account for the decline in Spatial Span Total Score. Spatial Span Forward score was not as good a predictor of severity in that reduction in score for Spatial Span Forward remains relatively stable regardless of level of impairment. Spatial Span Backward performance was …

Attention-deficit/hyperactivity disorder (ADHD) is surrounded by confusion and controversy regarding its definition, course, etiology and treatment. Among adults, ADHD is rarely considered a diagnostic reality of primary importance and is often overlooked. This study provides descriptive validity for adult ADHD in distinguishing it from controls, and identifying both a pure condition and one wrought with comorbidity.

The primary purpose of the study was to quantify the characteristics of certain self cognitions that occur in depressed adolescents. A secondary purpose was to assess the change that occurs in these self cognitions during a depressive episode. The intervention, in the form of guided imagery about a previous drug-using episode, was used to induce a mood change. The REP, a Personal Construct Theory measure, and the Beck Depression Inventory were used in a repeated measures design.

One hundred persons applying for services with the Texas Rehabilitation Commission with reported disabilities of alcohol/substance abuse or back injury/pain were selected for study. Subjects were assigned to two groups (alcohol or back) according to their reported disability. They were tested within one week of application and after 60 days were checked to see what rehabilitation status they were in to determine success or failure. Alcohol clients were administered the Health Attribution Test (HAT), 16PF, and an Alcohol Imagery questionnaire developed for this study. Back clients were administered the HAT, 16PF, and Pain Drawings. Statistical procedures including Pearson correlation, stepwise discriminant analysis, and discriminant analysis were performed. The HAT Internal Factor showed a significant relationship to rehabilitation success or failure and the 16PF motivation indices approached significance. The discriminant analysis demonstrated that success or failure could be predicted at a significant level using these measures. Issues of practicality in using these instruments (particularly imagery measures) in a rehabilitation counseling practice were noted.

It has been hypothesized that a disproportionate percentage of the blind population are learning disabled. In the past, norms and technology were not available to assess in a cost effective manner the blind client's neuropsychological functioning. Norms for the Wide Range Achievement Test - Revised (WRAT-R2) are now available for a blind population without any neuropsychological dysfunctioning. This study utilized the adapted WRAT-R2 and the Comprehensive Vocational Evaluation System (CVES), a neuropsychological test battery adapted for the blind, to investigate the possibility that learning disabilities are present in the adult blind population. Suspected learning disabled, blind subjects were compared with normal blind subjects. There were significant neuropsychological differences between the two groups.