The purpose of the current study was to explore the relationship between cognitive status and depression in a sample of geriatric patients. Participants included 282 geriatric patients ranging in age from 65 to 96 years who were classified according to diagnosis as: DAT, VaD, MCI, and Norm. All were referred for neurocognitive testing from the Geriatric Assessment Program (GAP) at the University of North Texas Health Science Center (UNTHSC) in Fort Worth, Texas. This study sought to identify factor structures for two versions of the GDS using a geriatric sample of cognitively impaired and intact patients. It then compared these factors to each other to determine whether the GDS-15 is truly a shorter version of the GDS-30. These were then compared to a previously determined factor structure. This study explored whether the four-factors of the GDS-30 are able to differentiate cognitive diagnostic groups. Further, this study sought to identify whether the severity of cognitive decline impacted GDS factor score for each of the cognitively impaired groups. Results revealed a two-factor model of the GDS - 15 and a four-factor model with the GDS - 30. The GDS-15 factors did not differ from the first two factors of the GDS-30. Comparison …

The purpose of the present study was to compare the number of perseverations on fused (no delay) versus unfused (0.5 msec delay) CV-DL tasks with measures on a battery of executive functions across three groups: Schizophrenics (SCZ), Manic-Depressives (MD), and normal controls (NC).

The purpose of the present study was to investigate the psychophysiological effects of exercise on measures of cardiovascular fitness, depression, self-esteem, and anxiety. The 1.5 mile run (Cooper, 1972) was used to determine changes in cardiovascular fitness. The Zung Self-Rating Depression Scale was used to measure varying levels of depression. The Rosenberg Self-Esteem Scale was used to measure self-esteem. The Spielberger State-Trait Anxiety Inventory was used to measure state anxiety. An Electromyographic Assay and Digital Skin Temperature were performed on the Experimental and Corrective Therapy Groups in order to measure physiological concomitants of anxiety. A Body Composition Assay was performed in order to measure changes in body composition.

The purpose of this study was to validate the Spanish version of the Dallas Pain Questionnaire (DPQ). Not only does the DPQ offer the potential of statistical and clinical diagnostic value but also is easily interpretable across cultural lines. No such instrument has presently been validated for the Mexican-American population. A total of 81 Spanish speaking subjects participated in this study. Of these subjects, 56 were classified as chronic pain patients by nature of their medical diagnosis and duration of pain. The 25 normal subjects were family members of the chronic pain patients and members of the Northern New Mexico Hispanic community chosen at random. Hypothesis one predicted that reliability would be obtained on Spanish speaking populations based on test-retest with correlation coefficients of the items. The second hypothesis predicted that the Spanish DPQ would have content validity or consistent internal structure on those items that measure the trait or behavior of interest based upon factor analysis approaches and internal consistency measures. Hypothesis three predicted that the Spanish version of the DPQ would significantly correlate with the English version of the DPQ on all four factors. All four hypotheses were supported. The Spanish DPQ showed reliability over time based on …

The purpose of the study was to determine the point prevalence of cognitive dysfunction in patients with systemic lupus erythematosus (SLE) and to investigate its association with corticosteroids and depression. The severity of dysfunction and the pattern of cognitive changes were examined. This study hypothesized that cognitive dysfunction is common in SLE and many previous studies have underestimated its prevalence, partially due to using limited neuropsychological batteries and insensitive test instruments. It was further hypothesized that the pattern of cognitive changes in SLE patients will resemble that observed in subcortical dementias.

The Behavioral Medicine Questionnare (BMQ) is a 44- item instrument administered via a computer CRT display or pencil and paper. The BMQ was designed to help primary care physicians treating spinal disorders to screen for emotional factors which warrant further psychological evaluation. The test is composed of three scales: Anxiety, Depression, and Somatization. Concurrent validity for each scale was determined through comparisons with subject (n = 133) scores on clinician judgement ratings, pain drawings, and the MMPI. The psychometric properties of the test were supported through statistical analysis. Significant correlations were found between the BMQ, MMPI, and clinician ratings, with the latter showing relationships of lesser strength. The only significant correlation to subject generated pain drawings was to the BMQ depression scale. Analysis indicated the need for seperate norms for males and females. Further research is needed to facilitate measurement and interpretation of the BMQ.

Individuals with attention deficit hyperactivity disorder (ADHD) with and without a learning disorder (LD) and a control group of clinically referred individuals with behavioral problems were compared on four neuropsychological tests of frontal lobe functioning. Test results were collected to examine if ADHD individuals with and without LD have deficits in frontal lobe functioning. Two age groups were used to examine developmental differences. In the six to ten age group there were 27 ADHD, 17 ADHD/LD and seven other clinically referred individuals. In the 11 -20 age group there were 12 ADHD, 23 ADHD/LD and 24 other clinically referred individuals. The ADHD and ADHD/LD groups performed at a lower level than the other diagnostic group on the freedom from distractibility factor of the WISC-R and the omission and commission errors of the Gordon Diagnostic system. Differences for the ADHD and ADHD/LD groups were also found on the number of correct responses for the Gordon Diagnostic system, the Speech Sounds test and the Seashore Rhythm test. The developmental differences that were found were not influenced by diagnosis. The deficits that the ADHD individuals with and without LD demonstrated were not affected by age.

This investigation focused on two major areas of investigation, (a) the differentiation of functions between the two cerebral hemispheres and (b) the effectiveness of electromyographic biofeedback versus relaxation tape input as methods of lowering levels of arousal. The purpose of the study was to evaluate the differential effects of EMG biofeedback and relaxation tape input to the right ear only, to the left ear only and to both ears in a strongly lateralized population. Subjects were 56 students recruited from undergraduate psychology classes. To be included in the study, subjects had to score at minimum, and Edinburgh Handedness Inventory Laterality Quotient of 68, Declie = Right 3, and had to demonstrate a right ear advantage on the Dichotic Listening Task for Words.

The purpose of the present study was to determine if psychological stress, defined as academic examination stress, would systematically produce changes in immune parameters (immunoglobulin concentration) and psychological functioning. It was hypothesized that as examination stress occurred there would be an effect on immunological function consistent with heightened psychological activity/stress. Subjects were 23 master's and doctoral students in psychology who volunteered for the research project. All subjects were administered a series of psychological tests to measure stress, personality factors, emotional states, and anxiety levels. All tests were administered and.blood samples drawn over a period of 15 months across two lowstress and two high-stress periods. Immunological tests included white blood cell (WBC) differential count and radial immunodiffusion (RID) for the determination of concentration of different immunoglobulin classes (IgA, IgG, IgM) in serum. Data were treated to a one-way analysis of variance (ANOVA) with repeated measures, t /test for correlated samples correlational matrix between variables across assessments and discriminant function analysis. Results showed (1) increased immunoglobulin levels during periods of stress; (2) immunoglobulin G most consistently related to stress and probably most indicative of the stressed condition and biological resistance to stress; (3) anxiety related to external events; (4) increase in anxiety …

This study examined the effect of neurotoxic chemical exposures on brain processes using Single Photon Emission Computed Tomography (SPECT). A control group carefully screened for good health and minimal chemical exposures was compared to two groups of patients diagnosed with health problems following exposure to pesticides or to organic solvents.

The purpose of the present study was to investigate cognitive functioning in a group of 30 chronic pain patients (CPG) as compared to a group of 39 acute pain patients (APG). In order to assess cognitive performance, certain subtests were selected from the McCarron-Dial System (MDS) of Neuropsychological Evaluation. Specifically, a measure of haptic discrimination was used along with the Bender Visual Motor Gestalt Test. As such, completion of these subtests required a cortically mediated, central nervous system processing of sensory information. This particular method of assessment was chosen because it provided a nonverbal measure of higher-order cognitive performance. Additionally, the haptic measure provided separate scores for right and left hemispheric functioning. Data analysis revealed significantly poorer Bender performance among CPG members (t(69) = -5.09, E - •0004, two tailed). Further data analysis revealed that the CPG performed significantly poorer on certain of the haptic discrimination subtests. Specifically, both texture and configuration scores for the right hemisphere were significantly lower among CPG members (texture, p = -042 and configuration, p = .002). Subsequent analyses were conducted to determine predictive relationships between important variables. These data are discussed in terms of their clinical significance and importance for future research.

It is believed by many researchers that little attention has been given to patients' perceptions of the impact of chronic pain on their lives. In recognition of this need, G. Frank Lawlis, C. Edward McCoy, and David K. Selby developed the Dallas Pain Questionnaire (DPQ) to assess the amount of chronic pain that affects four aspects (daily activities, work-leisure activities, anxiety-depression, and social interest) of the patients' lives. The present study, conducted to validate the DPQ's statistical properties, first reviews the literature addressing the various theories and varieties of pain, its opiates, and the two current approaches to quantify pain. This study included a total of 143 subjects. Clinical subjects were 104 inpatients in the Spinal and Chronic Pain Center at Medical Arts Hospital and 15 chronic pain outpatients released to work. Normal subjects consisted of staffing personnel (n = 13) and flight assistance employees (U = 11)- Both clinical and normal groups completed the DPQ. The Minnesota Multiphasic Personality Inventory (MMPI) was administered only to the clinical population. Results suggest that the DPQ is both externally reliable (stability reliability coefficient of .970) as well as an internally consistent instrument. Two factors emerged from factor structure analysis. Factor one (63.2% …

The effects of a computer program (Health Imagery Technology Systems, HITS) designed to promote attitude and cognitive changes through elicitation of evoked response potentials were evaluated with chronic pain patients. A treatment and control group were used for comparison (52 patients, 22 females, 32 males, mean ages 47). Wechsler Adult Intelligence Scale-Revised subtests, a Semantic Differential scale, the Health Attribution Test, an imagery protocol, the McCoy-Lawlis Pain Drawing, and the Zung Depression scale were used at admission and discharge to measure change. A pre- post-mood thermometer was used with the treatment group. The hypotheses that the treatment group would show significant changes on these measures were tested with a two group repeated measures analysis of variance design. No significant changes were noted for either group on the intellectual measures, on health attitudes, or reports of pain. The similarities subscale showed significant within group variance (F = 5.46, p < .023). One bipolar adjective pair indicated significant differences (F = 4.79, p < .035), possibly a result of chance. One of seven imagery measures suggested a significant improvement in strength of imagery for the treatment group (F = 18.2, p < .00008). Both groups showed significantly improved imagery of body defenses …

Relationships of negative psychological conditions with general status of cell-mediated and humoral immune systems were investigated. A unique approach was utilized in that indexes representing multiple aspects of each branch of the immune system were employed to better indicate general immunological status. Differences in emotion-immune interactions between males and females were demonstrated. Results indicated a positive relationship between Trait Anger and Cell-Mediated Immunological Index. Particular criticisms of previous psychoneuroimmunological research were met by addressing sex differences and differences in various conditions of anger and depression, as well as through assessment of cumulative effects of negative emotions on immune system status. Directions for future research in eddressing similar issues are suggested. In general, results provide support for validity of mindbody interactionism and imply the need for revision of standard medical and psychological treatment.

This study was an investigation of the effects of physiologically-oriented mental imagery on immune functioning. College students with normal medical histories were randomly selected to one of three groups. Subjects in Group 1 participated in short educational training on the production of secretory immunoglobulin A. They were then tested on salivary IgA, skin temperature and the Profile of Mood States (POMS) before and after listening to a 17-minute tape of imagery instructions with specially-composed background "entrainment" music, designed to enhance imagery. Subjects in Group 2 (placebo controls) listened to the same music but received no formal training on the immune system. Group 3 acted as a control and subjects were tested before and after 17 minutes of no activity. Treatment groups listened to their tapes at home on a bi-daily basis for six weeks. All groups were again tested at Weeks 3 and 6. Secretory IgA was analyzed using standard radial immuno-diffusion techniques. Repeated measures analyses of variance with planned orthogonal contrasts were used to evaluate the data. Significant overall increases (p < .05) were found between pre- and posttests for all three trials. Groups 1 and 2 combined (treatment groups) yielded significantly greater increases in slgA over Group 3 …

The present study investigated the influence of a brief, intensive biofeedback-assisted imagery training regimen on psychological, physiological and neuroendocrinological measures of pain and stress in injury related chronic pain patients. The subjects were 36 patients (myelography examcandidates) who were assigned to the imagery or wait-list control group by order of referral presentation and to formulate equivalent groups.

This investigation was an attempt to replicate and expand previous research which suggested that laterality of electromyographic biofeedback input had a significant effect in lowering frontalis muscle activity. In 1984 Ginn and Harrell conducted a study in which they reported that subjects receiving left ear only audio biofeedback had significantly greater reductions in frontalis muscle activity than those receiving right ear only or both ear feedback. This study was limited to one biofeedback session and subjects were selected based on demonstration of right hand/ear dominance. The purpose of the present study was to determine whether the left ear effect reported by Ginn and Harrell could be replicated. Furthermore, the current investigation sought to extend the previous finding to left handed subjects and explore the stability of the effect, if found, by adding a second biofeedback session. Subjects were 96 students recruited from undergraduate psychology classes. They were screened for handedness by the Edinburgh Handedness Inventory which resulted in identification of 48 right handers and 48 left handers. Subjects were randomly assigned to one of four groups consisting of left ear feedback, right ear feedback, both ears feedback, and controls. This resulted in eight conditions. Analysis of variance of microvolt changes …

The purpose of the present study was to ascertain if environmentally sensitive patients would demonstrate different memory deficit patterns than psychiatric patients on objectively measurable memory tasks. One-hundred sixteen patients were surveyed; 56 environmentally sensitive patients were compared to 60 psychiatric patients. All subjects were administered a Wechsler Adult Intelligence Scale-Revised screen, the Wechsler Memory Scale-Revised and the Harrell-Butler Comprehensive Neurocognitive Screen after history of head injury was ruled out. Results indicate a significantly different pattern of memory dysfunction between the environmental patients and the psychiatric patients, indicating two different etiologies. A screening device derived from the coefficients from a Canonical Analysis is proposed to distinguish between the two populations in the absence of blood serum levels of environmental toxins or poisons. The detrimental effects of misdiagnosis and the beneficial effects of accurate diagnosis of environmental illness are discussed.

The present study was undertaken (1) to compare the connotative meanings criminals attach to a sampling of concepts with those meanings attached by noncriminals, and (2) to examine the possible relationship between moral development and criminal behavior. One hundred thirty four male subjects completed the Wide Range Achievement Test- Revised (Reading Section); a personal data sheet; the Ammons Quick Test-Form I; the Criminal Semantic Inventory; the Test for Criminal Cognitions; and the Sociomoral Reflection Questionnaire. Subjects were divided into four groups (Noncriminals, Against Person Group, Against Property Group, and Against Statute Group) on the basis of history of criminal conviction. A one-way MANOVA was conducted on each of the 16 concepts under investigation. Significant differences were found for five concepts. In addition, criminals were found to differ significantly from noncriminals on level of moral development.

This study examined the effects of self-monitoring behavior and health locus of control on improvement in a work hardening program. The subjects included 22 male and 18 female outpatients in a hospital-based rehabilitation program. Subjects were classified as having an internal or external health locus of control, and were randomly assigned to either a self-monitoring or a non-self-monitoring group. Improvement was assessed via objective performance data and self-ratings of perceived improvement. The results indicated that individuals identified as having an internal health locus of control did not show greater gains in physical functioning or perceived improvement relative to externally oriented individuals. Additionally, those subjects participating in self-monitoring activities were no different from non-self-monitoring subjects in terms of improvement in exercise activities or perceived improvement. The results also indicated no interaction between health locus of control and the presence or absence of self-monitoring. It was suggested that other factors such as workman's compensation, pain patient characteristics, low self-concept, and severe stress may have proved more powerful influences on patient improvement than internal health locus of control or self-monitoring. It was also suggested that rehabilitation programs might benefit from creating structured environments in which patients receive frequent staff feedback and reinforcement for …

The blind have generally been considered to be a homogeneous population whose deficits arise from an interaction of loss of vision, age of onset and socialization. Sequelae are posited to exist merely due to the limiting effects of blindness on experience. This is believed to affect all blind persons equally regardless of cause of blindness provided that independent secondary disabilities do not exist. This study investigated the possibility that different causes of blindness are related to specific neuropsychological deficits which cannot be explained by the mere presence of blindness. It was found that neuropsychological differences existed among specific sub-populations of blind persons. These results suggested that the cause of blindness may be a marker for specific Central Nervous System involvement.

In an attempt to determine the normative levels in health attribution and emotional, intellectual, and neuromuscular functioning in the parkinsonian population, 31 diagnosed parkinsonian volunteers recruited from exercise classes and/or organizations were tested. Health attribution was measured by the Health Attribution Test (HAT), personality factors by the Clinical Analysis Questionnaire (CAQ), general intellectual level by the Peabody Picture Vocabulary Test- Revised (PPVT-R) and the Intellectual Processes subscale of the Luria-Nebraska Neuropsychological Battery (Luria- Intelligence), and neuromuscular functioning by the McCarron Assessment of Neuromuscular Development (MAND) and Bender- Gestalt (BVMGT). Controls for comparisons were obtained from the clinical ecology population and normals for personality traits and the nonspecific neurologically impaired, healthy aging populations, and normals for intellectual and neuromuscular functionings. Chi-square and t-tests were computed on the data. Results indicated that the parkinsonians manifest less lower body strength (£ < .01), poorer balance with eyes closed (JD < .01), and slower fine motor speed (p < .05) than normals. The parkinsonians function significantly better in areas involving upper body coordination (p < .01, £ < .05) , slow-controlled movements (g.< .001), BVMGT (p < .05), and PPVT-R (p < .01) than the nonspecific neurologically impaired. On the Luria-Intelligence, 21 percent of …

To investigate the possibility that chronic diabetes mellitus was related to specific neuropsychological deficits, cognitive functioning was measured in subjects with diabetic retinopathy (without secondary disabilities), and in subjects classified as normal blind adults (also without secondary disabilities). The scores for the two groups were then compared.

The McCarron-Dial System (MDS) has successfully predicted vocational and independent living outcomes with neuropsychologically disabled individuals receiving rehabilitation services. In addition, preliminary validation studies suggest that the abbreviated MDS is useful for clinical neuropsychological diagnosis. The present study represents part of an ongoing research project aimed at validating the expanded version of the MDS for diagnosis of neuropsychological dysfunction. Specifically, it was hypothesized that the expanded MDS would be able to accurately discriminate between brain-damaged and non-brain-damaged individuals. Accurate diagnosis facilitates rehabilitation efforts for individuals with neuropsychological disabilities and the data profile provided by the expanded version of the MDS can consequently form the basis from which more complete individual treatment and rehabilitation plans can be conceptualized.