Louise Villejo was born in 1953 in San Antonio, TX. She migrated to Houston when she was three years old and grew up witnessing white flight in the Sunnyside neighborhood in Houston. After attending Catholic schools, she become involved in the University of Houston Mexican American Youth Organization. Villejo talks about how she was a leader in Mujeres Unidas, an organization where Chicana feminists addressed women's issues and developed Teatro Mujeres Unidas. At this time, she was involved in cross-racial efforts as a ethnic student council representative. Villejo also discusses her participation in and experiences with some of the major Chicana and mainstream feminist conferences, including the 1975 Chicana Identity Conference, the 1975 International Women's Year Conference in Mexico City, and the 1977 International Women's Year Conference. She describes the Jose Campos Torres incident and the Moody Park Rebellion. She ends the interview by talking about her involvement in Latina/o patient advocacy, something she has dedicated her adult life to.