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31,148 Matching Results
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Investigating Novel Streptomyces Bacteriophage Endolysins as Potential Antimicrobial Agents
As antibiotic resistance has become a major global threat, the World Health Organization has urgently called scientists for alternative strategies for control of bacterial infections. Endolysin, a protein encoded by a phage gene, can degrade bacterial peptidoglycan (PG). Currently, there are three endolysin products in the clinical phase. We, thus, are interested in exploring novel endolysins from Streptomyces phages as only a few of them have been experimentally characterized. Using bioinformatics tools, we identified nine functional domain groups from 250 Streptomyces phages putative endolysins. NootNoot gp34 (transglycosylase; Nt34lys), Nabi gp26 (amidase; Nb26lys), Tribute gp42 (PGRP; Tb42lys), and LazerLemon gp35 (CHAP; LL35lys) were selected for experimental studies. We hypothesized that (1) the proteins of interest will have the ability to degrade PG, and (2) the proteins will be potential antimicrobial agents against ESKAPE safe relatives. The results showed that LL35lys, Nb26lys and Tb42lys exhibit PG-degrading activity on zymography and hydrolysis assay. The enzymes (400 µg/mL) can reduce PG turbidity to 32-40%. The killing assay suggested that Tb42lys possess a boarder range (Escherichia coli, Pseudomonas putida, Acinetobacter baylyi and Klebsiella aerogenes). While Nb26lys can attack Gram-negative bacteria, LL35lys can only reduce the growth of the Gram-positive strains with an MIC90 of 2 …
Date:
December 2023
Creator:
Maneekul, Jindanuch
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Resident Satisfaction Indicators in Long-Term Care Settings
Due to an increasingly aging population and long-term care available, the number of older adults seeking long-term care facilities is growing. Resident satisfaction indicators have become essential measurements of service quality. However, few studies have investigated the evidence on prevalent resident satisfaction indicators and associated factors. In order to understand what are the types of resident satisfaction measurements utilized in long-term care facilities in the United States and how these types of care services influence resident satisfaction, the researcher conducted the first study, which consists of a systematic scoping review by summarizing the evidence on the types of resident satisfaction indicators utilized in long-term care settings in the United States. The second study completed a further systematic review to summarize how nursing assistants impact resident satisfaction in long-term care settings.The third study aims to translate and validate a Chinese version of the resident satisfaction assessment based on the Ohio Long-term Care Resident Satisfaction Survey (OLCRSS). The fourth study will apply hierarchical regression to predict older adults' satisfaction with individual factors and care services factors in long-term care settings. The dissertation provided a holistic solution to measure resident satisfaction in long-term care settings, assist health providers in meeting the resident`s needs …
Date:
May 2023
Creator:
Li, Xiaoli
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Philosophical Society of Texas, Proceedings of the Annual Meeting: 2021
Proceedings of the annual meeting of the Philosophical Society of Texas held virtually on February 5, including a list of attendees, text of addresses, changes to membership, and biographical information about members who have passed. The conference theme was "Lone Star Gazing: Texas Mid-21st Century."
Date:
2023
Creator:
Philosophy Society of Texas
Object Type:
Book
System:
The Portal to Texas History
The Weston Post (Weston, Tex.), Issue No. 9, Winter 2022
Quarterly newsletter from Weston, Texas that includes news and information about the community.
Date:
Winter 2022
Creator:
Yurkovitch, Brittany
Object Type:
Journal/Magazine/Newsletter
System:
The Portal to Texas History
Medicago truncatula NPF1.7: Structure-Function Assessment and Potential as a Phytohormone Transporter
In Medicago truncatula, the MtNPF1.7 transporter has been shown to be essential for root morphology and nodulation development. The allelic MtNPF1.7 mutants, Mtnip-1 (A497V), Mtnip-3 (E171K), and Mtlatd (W341STOP), show altered lateral root growth and compromised legume-rhizobium symbiosis. To assess the role of a series of distinct amino acids in the transporter's function, in silico structural predictions were combined with in planta complementation of the severely defective Mtnip-1 mutant plants. The findings support hypotheses about the functional importance of the ExxE(R/K) motif including an essential role for the first glutamic acid of the motif in proton(s) and possibly substrate transport. The results also question the existence of a putative TMH4-TMH10 salt bridge, which may not form in MtNPF1.7. Results reveal that a motif conserved among MFS proteins, Motif A, is essential for function. Hypothetically, the Motif A participates in intradomain packing of transmembrane helices and stabilizing one conformation during transport. The mutated valine (A497V) in Mtnip-1 may interfere with the lateral helix. Mutating a residue (L253) on the lateral helix with reduced side chain restored Mtnip-1 function. The predicted residue (Q351) for substrate binding is not essential for protein function. To probe the possibility that MtNPF1.7 transports auxin, two heterologous …
Date:
December 2022
Creator:
Yu, Yao Chuan
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
The Naming Commission - Final Report to Congress, Part I: United States Army Bases
Report summarizing the recommendations of The Naming Commission's findings regarding army bases as mandated by the National Defense Authorization Act for Fiscal Year 2021, which mandates the removal of names, symbols, displays, monuments and paraphernalia that honor or commemorate the Confederate States of America. "Part 1 of the three-part Naming Commission Final Report .... recommends new names for nine military bases (Fort Hood, Texas; Fort Bragg, North Carolina; Fort Rucker, Alabama; Fort Polk, Louisiana; Fort Benning and Fort Gordon in Georgia; and Fort A. P. Hill, Fort Lee and Fort Pickett in Virginia), the disposition of all Confederacy-affiliated and named Department of Defense assets on those bases, and additional guidance for the nine bases." [Executive Summary, Page 2]
Date:
August 2022
Creator:
United States. Naming Commission.
Object Type:
Report
System:
The UNT Digital Library
The Express-Star (Chickasha, Okla.), Ed. 1 Thursday, November 11, 2021
Triweekly newspaper from Chickasha, Oklahoma that includes local, state, and national news along with advertising.
Date:
November 11, 2021
Creator:
unknown
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
[College of Liberal Arts and Social Sciences and Frank W. and Sue Mayborn School of Journalism Spring 2021 virtual recognition ceremony]
Video recording of Spring 2021 College of Liberal Arts and Social Sciences and Frank W. and Sue Mayborn School of Journalism recognition ceremony. The ceremony was aired virtually on Friday, April 30 at 1 p.m. The in-person commencement ceremony for the College of Liberal Arts and Social Sciences and Frank W. and Sue Mayborn School of Journalism was held at Apogee Stadium on Friday, April 30 at 7 p.m. The ceremony includes opening and closing remarks by the Executive Dean of the College of Liberal Arts and Social Sciences Dr. Tamara L. Brown. Graduates of the Bachelor's program are recognized with their names shown on-screen individually in the order of degree earned.
Date:
April 30, 2021
Creator:
University of North Texas.
Object Type:
Video
System:
The UNT Digital Library
Fort Worth Stories
Access:
Use of this item is restricted to the UNT Community
Fort Worth Stories is a collection of thirty-two bite-sized chapters of the city’s history. Did you know that the same day Fort Worth was mourning the death of beloved African American “Gooseneck Bill” McDonald, Dallas was experiencing a series of bombings in black neighborhoods? Or that Fort Worth almost got the largest statue to Robert E. Lee ever put up anywhere, sculpted by the same massive talent that created Mount Rushmore? Or that Fort Worth was once the candy-making capital of the Southwest and gave Hershey, Pennsylvania, a good run for its money as the sweet spot of the nation? A remarkable number of national figures have made a splash in Fort Worth, including Theodore Roosevelt while he was President; Vernon Castle, the Dance King; Dr. H.H. Holmes, America’s first serial killer; Harry Houdini, the escape artist; and Texas Guinan, star of the vaudeville stage and the big screen. Fort Worth Stories is illustrated with 50 photographs and drawings, many of them never before published. This collection of stories will appeal to all who appreciate the Cowtown city.
Date:
February 2021
Creator:
Selcer, Richard F.
Object Type:
Book
System:
The UNT Digital Library
[Commencement Program for University of North Texas, Fall 2020]
Commencement program for the fall 2020 graduating class of the University of North Texas, held at Apogee Stadium on Sunday, November 22, 2020. The program contains the order of service and a list of graduates for the baccalaureate, master's, and doctoral degrees.
Date:
November 22, 2020
Creator:
University of North Texas
Object Type:
Pamphlet
System:
The UNT Digital Library
The Baytown Sun (Baytown, Tex.), Vol. 100, No. 130, Ed. 1 Sunday, August 23, 2020
Triweekly newspaper from Baytown, Texas that includes local, state, and national news along with advertising.
Date:
August 23, 2020
Creator:
Bloom, David
Object Type:
Newspaper
System:
The Portal to Texas History
The Earps Invade Southern California: Bootlegging Los Angeles, Santa Monica, and the Old Soldiers’ Home
Access:
Use of this item is restricted to the UNT Community
Most readers of the Wild West know Wyatt Earp, Virgil Earp, and Morgan Earp for the famous shootout on the streets of Tombstone, Arizona. But few know the later years of the close-knit Earp family, which revolved around patriarch Nicholas Earp, and their last push at a major monetary coup in Los Angeles. By 1900 a newly established Old Soldiers’ Home was in place at Sawtelle (between Santa Monica and Los Angeles), with thousands of veterans earning monthly pensions, but in an environment where alcohol was prohibited. Enter the Earps and their “blind pig” (illicit alcohol sales) scheme. Two of the Earps, Nicholas and son Newton, were enrolled in the Soldiers’ Home, and Newton’s far more famous half-brothers Wyatt and Virgil showed up from time to time, but the star of the operation was older brother James. Booze would flow, the pension money would be “dispersed about,” and jails were sometimes filled, as the Earps and several other men on the make competed for the veterans’ money. We are also reintroduced to Old West figures such as “Gunfighter Surgeon” Dr. George Goodfellow, “Silver Tongued Orator” Thomas Fitch, millionaire George Hearst, detective J.V. Brighton, Lucky Baldwin, and many other well-known westerners …
Date:
July 15, 2020
Creator:
Chaput, Donald & De Haas, David D., 1956-
Object Type:
Book
System:
The UNT Digital Library
Catalog of the University of North Texas, 2020-2021, Graduate
The UNT Graduate Bulletin includes information about class offerings as well as "policies, regulations, procedures and fees in effect at the time [the] publication went to press"
Date:
July 2020
Creator:
University of North Texas
Object Type:
Book
System:
The UNT Digital Library
Analysis of Interrelationships between Climate Change and Cotton Yield in Texas High Plains
The Texas High Plains produces the most substantial amount of cotton in Texas. The region is a semi-arid area with limited precipitation, and it is, therefore, susceptible to climate change. Cotton production in the Texas High Plains is mostly dependent on irrigation to increase yield. The overall goal of this research was to study the interrelationships between climate change and cotton yield using correlation analysis and also to study how climate has changed in the region using trend analysis. A three-decade data (1987-2017) was analyzed to establish the relationship between climate change and cotton and also to determine how climate has changed in the area over the last 30 years. The research used precipitation and temperature data to assess climate change.The results of this research showed that annual mean temperature has lesser impacts on cotton yield, and the correlation between annual precipitation and cotton yield is insignificant. It also found out that high rates of temperature at the boll opening stage of cotton growth results in decreased cotton yield and that at the boll development and boll opening stages, precipitation is needed. Again, the research indicated that, on average, there had been a significant increase in temperature, but precipitation trends …
Date:
May 2020
Creator:
Sarbeng, Lorenda
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
Annotated Texas Family Code 2020
Annotated Text of the Texas laws related to marriage, family, children, parent-child relationships, and other relevant legal issuances.
Date:
2020
Creator:
State Bar of Texas
Object Type:
Book
System:
The Portal to Texas History
Exploring the Utility of Metadata Record Graphs and Network Analysis for Metadata Quality Evaluation and Augmentation
Article discussing the effectiveness of network analysis for evaluating digital library metadata records. It provides count- and value-based statistics as well as network metrics for each of the two collections identified for this research and compares the usefulness of various data values for metadata quality analysis.
Date:
2020
Creator:
Phillips, Mark Edward; Zavalina, Oksana & Tarver, Hannah
Object Type:
Article
System:
The UNT Digital Library
The Effectiveness of Child Parent Relationship Therapy (CPRT) for Fathers
High levels of quality father involvement in childhood are associated with children's socio-emotional, cognitive, and behavioral wellbeing. However, fathers can experience difficulty in building positive relationships with their kids due to work-life balance, lack of relational experience, and other life stressors. The purpose of this study was to assess the effectiveness of child-parent relationship therapy (CPRT) on fathers' parental empathy, parental stress, and child behavior problems. Though an abundance of literature exists to support the efficacy of CPRT, this was the first study to include a randomized controlled design with an all-male sample. This was also the first CPRT study to include both English and Spanish speaking fathers with intervention offered in both languages. Participants were 30 fathers (22 English, 8 Spanish; 53% Latino, 40% Caucasian, 7% Asian) with children between the ages of 3 and 10 (60% male, 40% female; 57% Latino/a, 37% Caucasian, 6% Asian). Fathers were randomly assigned to the experimental group (CPRT) (n = 14) or waitlist control group (n = 16). Results from 2 (Group) by 2 (Time) repeated measures ANOVAs did not yield statistically significant interaction effects on the dependent variables. However, results indicated a statistically significant main effect for time on each dependent …
Date:
December 2019
Creator:
McClintock, Damian Gearld
Object Type:
Thesis or Dissertation
System:
The UNT Digital Library
South Texas Catholic (Corpus Christi, Tex.), Vol. 54, No. 11, Ed. 1, December 2019
Monthly newspaper from Corpus Christi, Texas published by the Diocese of Corpus Christi that includes news of interest to Diocese members along with advertising.
Date:
December 2019
Creator:
Cottingham, Mary
Object Type:
Newspaper
System:
The Portal to Texas History
Celebrating 20 Years of Genetic Discoveries in Legume Nodulation and Symbiotic Nitrogen Fixation
This article is a review cataloging and contextualizing all of the plant genes currently known to be required for SNF in two model legume species, Medicago truncatula and Lotus japonicus, and two crop species, Glycine max (soybean) and Phaseolus vulgaris (common bean). The authors also briefly consider the future of SNF genetics in the era of pan-genomics and genome editing.
Date:
October 24, 2019
Creator:
Roy, Sonali; Liu, Wei; Nandety, Raja Sekhar; Crook, Ashley; Mysore, Kirankumar S.; Pislariu, Catalina I. et al.
Object Type:
Article
System:
The UNT Digital Library
Bioactive glass coatings on metallic implants for biomedical applications
Article provides a detailed overview of the benefits and issues of metal alloys when used as biomedical implants and how they are improved by bioactive glass-based coatings for biomedical applications.
Date:
October 5, 2019
Creator:
Oliver, Joy-anne N.; Su, Yingchao; Lu, Xiaonan; Kuo, Po Hsuen; Du, Jincheng & Zhu, Donghui
Object Type:
Article
System:
The UNT Digital Library
The Henderson News (Henderson, Tex.), Vol. 90, No. 41, Ed. 1 Wednesday, August 7, 2019
Semiweekly newspaper from Henderson, Texas that includes local, state, and national news along with advertising.
Date:
August 7, 2019
Creator:
Moore, Dan & Mahoney, Kent
Object Type:
Newspaper
System:
The Portal to Texas History
The Henderson News (Henderson, Tex.), Vol. 90, No. 40, Ed. 1 Sunday, August 4, 2019
Semiweekly newspaper from Henderson, Texas that includes local, state, and national news along with advertising.
Date:
August 4, 2019
Creator:
Moore, Dan & Mahoney, Kent
Object Type:
Newspaper
System:
The Portal to Texas History
Catalog of the University of North Texas, 2019-2020, Graduate
The UNT Graduate Bulletin includes information about class offerings as well as "policies, regulations, procedures and fees in effect at the time [the] publication went to press"
Date:
July 2019
Creator:
University of North Texas
Object Type:
Book
System:
The UNT Digital Library
Gainesville Daily Register (Gainesville, Tex.), Vol. 129, No. 184, Ed. 1 Wednesday, May 22, 2019
Daily newspaper from Gainesville, Texas that includes local, state, and national news along with advertising.
Date:
May 22, 2019
Creator:
Einselen, Sarah
Object Type:
Newspaper
System:
The Portal to Texas History