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Two legume fatty acid amide hydrolase isoforms with distinct preferences for microbial- and plant-derived acylamides (open access)

Two legume fatty acid amide hydrolase isoforms with distinct preferences for microbial- and plant-derived acylamides

Article describes how analysis of FAAHs from multiple angiosperm species, which revealed two conserved phylogenetic groups that differed in key conserved residues in the substrate binding pocket. The authors combined computational and biochemical approaches to compare the structural and enzymatic properties of two FAAH isoforms in the legume Medicago truncatula designated MtFAAH1 MtFAAH2a.
Date: May 9, 2023
Creator: Arias-Gaguancela, Omar; Herrell, Emily; Aziz, Mina & Chapman, Kent Dean
System: The UNT Digital Library
Role of microRNAs and their downstream target transcription factors in zebrafish thrombopoiesis (open access)

Role of microRNAs and their downstream target transcription factors in zebrafish thrombopoiesis

Article describes how previous studies have shown that human platelets and megakaryocytes carry microRNAs suggesting their role in platelet function and megakaryocyte development. In their laboratory, the authors identified 15 microRNAs in thrombocytes using single-cell RNA sequencing.
Date: September 26, 2023
Creator: Qaryoute, Ayah Al; Fallatah, Weam; Dhinoja, Sanchi; Raman, Revathi & Jagadeeswaran, Pudur
System: The UNT Digital Library