This paper assesses the medical benefits and costs of both screening and hormone replacement therapy. It is divided into two volumes. This volume presents the results of a model that estimates the cost per year of life gained from osteoporosis screening and hormone replacement therapy in postmenopausal women.

This paper assesses the medical benefits and costs of both screening and hormone replacement therapy. It is divided into two volumes. This volume provides the basis for the assumptions about the costs and effects of screening and hormonal replacement therapy used in the cost-effectiveness model.

This background paper examines wastes generated by industrial activities that play a dominant role in our national economy-oil and gas production, mining and mineral processing, coal combustion, and manufacturing. In previous reports on municipal solid waste and medical waste, OTA examined other solid wastes not classified as hazardous.

This study provides a technical assessment of traditional desalination techniques that can be used for water treatment. These techniques include distillation, as well as more recently developed membrane processes. As part of this effort OTA held a one-day workshop on July 29, 1987, with desalination and water treatment experts to review the initial draft of this background paper and to discuss other areas of interest. The conclusions of these discussions are included in this background report.

This paper presents the status of national efforts to cleanup dioxin-contaminated sites and the technologies that have been used, proposed, and researched. It covers thermal and nonthermal treatment techniques as well as approaches such as stabilization and storage. It discusses the development of these technologies as well as advantages and disadvantages of their use.

This report analyzes universities’, companies’, and researchers’ experiences and perspectives since enactment of federal laws to enhance technology transfer—especially as it pertains to research funded by the National Institutes of Health and the Department of Energy, the agencies funding U.S. efforts in the Human Genome Project.

This paper examines the health services and economics literature to learn what is known about the effects of patient cost-sharing (that is, annual deductibles, coinsurance, copayments, and out-of-pocket maximurns) on patients’ use of health care services, on plan expenditures, and on patients’ health outcomes.

This background report responds to a request by the Subcommittee on Water and Power Resources of the House Committee on Interior and Insular Affairs. The subcommittee asked that OTA review the health effects of high-voltage transmission lines. To provide background information for its assessment on electric power wheeling, OTA contracted with the Carnegie-Mellon University.

This report reviews how bioenergy crops could potentially affect soil quality and soil erosion, water quality, air quality, habitat for a variety of species, and the global environment.

This report focuses on the following two questions for the U.S. fusion energy program. First, what is the role of the Tokamak Physics Experiment (TPX), an approximately $700 million fusion reactor currently awaiting a congressional decision to begin construction? Second, what is the role of alternatives to the tokamak concept in a broad-based fusion energy program?

Adult education needs are difficult to define and difficult to meet; what constitutes adequate literacy changes continually as the demands facing individuals grow more complex. This report is an attempt to identify those capabilities, along with limitations, and outline how new information technologies can be marshaled to meet the goal of a fully literate citizenry.

This background paper, which describes the state-of the- art of identifying substances that can harm the immune system, represents one response to the committee’s request. Chapter 2 provides basic information about the principal components of the immune system and the general consequences that stem from perturbations to it. Chapter 3 describes methods for evaluating chemical immunotoxicity and reports on some known or suspected immunotoxicants. Chapter 4 summarizes Federal research and regulatory activities related to immunotoxicity.

This background paper describes what is known about the natural progression of the menopause and its effect on women’s health, hormone treatment and prescribing practices, alternative approaches, and research needs.