Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1 (open access)

Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1

Article discusses the role of Mg2+ in regulating vascular functions.
Date: July 30, 2019
Creator: Zhu, Donghui; You, Jing; Zhao, Nan & Xu, Huaxi
System: The UNT Digital Library
Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells (open access)

Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells

Article states that although KRASG12C inhibitors have shown promising activity in lung adenocarcinomas harboring KRASG12C, acquired resistance to these therapies eventually occurs in most patients. The authors report that the hedgehog signal is induced by KRASG12C inhibitors and mediates KRAS re-expression in cancer cells treated with a KRASG12C inhibitor.
Date: January 16, 2024
Creator: Lee, Chaeyoung; Yi, Jawoon; Park, Jihwan; Ahn, Byungyong; Won, Young-Wook; Jeon, JiHeung et al.
System: The UNT Digital Library