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Draft versus finished sequence data for DNA and protein diagnostic signature development
Sequencing pathogen genomes is costly, demanding careful allocation of limited sequencing resources. We built a computational Sequencing Analysis Pipeline (SAP) to guide decisions regarding the amount of genomic sequencing necessary to develop high-quality diagnostic DNA and protein signatures. SAP uses simulations to estimate the number of target genomes and close phylogenetic relatives (near neighbors, or NNs) to sequence. We use SAP to assess whether draft data is sufficient or finished sequencing is required using Marburg and variola virus sequences. Simulations indicate that intermediate to high quality draft with error rates of 10{sup -3}-10{sup -5} ({approx} 8x coverage) of target organisms is suitable for DNA signature prediction. Low quality draft with error rates of {approx} 1% (3x to 6x coverage) of target isolates is inadequate for DNA signature prediction, although low quality draft of NNs is sufficient, as long as the target genomes are of high quality. For protein signature prediction, sequencing errors in target genomes substantially reduce the detection of amino acid sequence conservation, even if the draft is of high quality. In summary, high quality draft of target and low quality draft of NNs appears to be a cost-effective investment for DNA signature prediction, but may lead to underestimation …
Date:
October 29, 2004
Creator:
Gardner, S N; Lam, M W; Smith, J R; Torres, C L & Slezak, T R
Object Type:
Article
System:
The UNT Digital Library
Use of Electrochemical Noise to Assess Corrosion in Kraft Continuous Digesters
Electrochemical noise (EN) probes were deployed in two continuous kraft digesters at a variety of locations representative of corrosion throughout the vessels. Current and potential noise, the temperature at each probe location, and the value of up to 60 process parameters (flow rates, liquor chemistry, etc.) were monitored continuously during each experiment. The results indicate that changes in furnish composition and process upsets were invariably associated with concurrent substantial changes in EN activity throughout the vessels. Post-test evaluation of the mild steel electrode materials in both vessels confirmed general corrosion of a magnitude consistent with historical trends in the respective vessels as well as values qualitatively (and semi-quantitatively) related to EN current sums for each electrode pair. Stainless steel electrodes representing 309LSi and 312 overlay repairs exhibited zero wastage corrosion--as did the actual overlays--but the EN data indicated periodic redox activity on the stainless steel that varied with time and position within the vessel. Little or no correlation between EN probe activity and other operational variables was observed in either vessel. Additional details for each digester experiment are summarized.
Date:
November 29, 2004
Creator:
Pawel, S.J.
Object Type:
Report
System:
The UNT Digital Library
Development of Novel Water-Gas Shift Membrane Reactor
None
Date:
December 29, 2004
Creator:
Ho, W. S. Winston
Object Type:
Report
System:
The UNT Digital Library
Development of Novel Water-Gas Shift Membrane Reactor
This report summarizes the objectives, technical barrier, approach, and accomplishments for the development of a novel water-gas-shift (WGS) membrane reactor for hydrogen enhancement and CO reduction. We have synthesized novel CO{sub 2}-selective membranes with high CO{sub 2} permeabilities and high CO{sub 2}/H{sub 2} and CO{sub 2}/CO selectivities by incorporating amino groups in polymer networks. We have also developed a one-dimensional non-isothermal model for the countercurrent WGS membrane reactor. The modeling results have shown that H{sub 2} enhancement (>99.6% H{sub 2} for the steam reforming of methane and >54% H{sub 2} for the autothermal reforming of gasoline with air on a dry basis) via CO{sub 2} removal and CO reduction to 10 ppm or lower are achievable for synthesis gases. With this model, we have elucidated the effects of system parameters, including CO{sub 2}/H{sub 2} selectivity, CO{sub 2} permeability, sweep/feed flow rate ratio, feed temperature, sweep temperature, feed pressure, catalyst activity, and feed CO concentration, on the membrane reactor performance. Based on the modeling study using the membrane data obtained, we showed the feasibility of achieving H{sub 2} enhancement via CO{sub 2} removal, CO reduction to {le} 10 ppm, and high H{sub 2} recovery. Using the membrane synthesized, we have obtained …
Date:
December 29, 2004
Creator:
Ho, W. S. Winston
Object Type:
Report
System:
The UNT Digital Library
The Optimist (Abilene, Tex.), Vol. 93, No. 12, Ed. 1, Wednesday, September 29, 2004
Tri-weekly student newspaper from Abilene Christian University in Abilene, Texas that includes local, state and campus news along with advertising.
Date:
September 29, 2004
Creator:
unknown
Object Type:
Newspaper
System:
The Portal to Texas History
Polk County Enterprise (Livingston, Tex.), Vol. 122, No. 9, Ed. 1 Thursday, January 29, 2004
Semi-weekly newspaper from Livingston, Texas that includes local, state and national news along with advertising.
Date:
January 29, 2004
Creator:
White, Barbara
Object Type:
Newspaper
System:
The Portal to Texas History
Altus Times (Altus, Okla.), Vol. 106, No. 25, Ed. 1 Thursday, April 29, 2004
Daily newspaper from Altus, Oklahoma that includes local, state, and national news along with advertising.
Date:
April 29, 2004
Creator:
Andrews, Mike
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Hudspeth County Herald and Dell Valley Review (Dell City, Tex.), Vol. 49, No. 61, Ed. 1 Friday, October 29, 2004
Weekly newspaper from Dell City, Texas that includes local, state, and national news along with advertising.
Date:
October 29, 2004
Creator:
Lynch, Mary Louise
Object Type:
Newspaper
System:
The Portal to Texas History
Cherokeean Herald (Rusk, Tex.), Vol. 155, No. 45, Ed. 1 Wednesday, December 29, 2004
Weekly newspaper from Rusk, Texas that includes local, state and national news along with extensive advertising.
Date:
December 29, 2004
Creator:
Whitehead, Marie
Object Type:
Newspaper
System:
The Portal to Texas History
The Oklahoma Daily (Norman, Okla.), Vol. 87, No. 129, Ed. 1 Monday, March 29, 2004
Student newspaper of the University of Oklahoma in Norman, Oklahoma that includes national, local, and campus news along with advertising.
Date:
March 29, 2004
Creator:
King, Christopher R.
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
15th Street News (Midwest City, Okla.), Vol. 34, No. 8, Ed. 1 Friday, October 29, 2004
Newspaper from Rose State College in Midwest City, Oklahoma that includes national, local, and campus news along with advertising.
Date:
October 29, 2004
Creator:
Delaney, Darcy
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Texas Jewish Post (Fort Worth, Tex.), Vol. 58, No. 5, Ed. 1 Thursday, January 29, 2004
Weekly Jewish newspaper from Fort Worth, Texas that includes local, state, and national news along with extensive advertising.
Date:
January 29, 2004
Creator:
Wisch, Rene & Wisch-Ray, Sharon
Object Type:
Newspaper
System:
The Portal to Texas History
Archer County News (Archer City, Tex.), No. 5, Ed. 1 Thursday, January 29, 2004
Weekly newspaper from Archer City, Texas that includes local, state, and national news along with advertising.
Date:
January 29, 2004
Creator:
Lewis, Shelley
Object Type:
Newspaper
System:
The Portal to Texas History
Perry Daily Journal (Perry, Okla.), Vol. 111, No. 83, Ed. 1 Thursday, April 29, 2004
Daily newspaper from Perry, Oklahoma that includes local, state, and national news along with advertising.
Date:
April 29, 2004
Creator:
Brown, Gloria
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Archer County News (Archer City, Tex.), No. 31, Ed. 1 Thursday, July 29, 2004
Weekly newspaper from Archer City, Texas that includes local, state, and national news along with advertising.
Date:
July 29, 2004
Creator:
Lewis, Shelley
Object Type:
Newspaper
System:
The Portal to Texas History
POST-PROCESSING ANALYSIS FOR THC SEEPAGE
This report describes the selection of water compositions for the total system performance assessment (TSPA) model of results from the thermal-hydrological-chemical (THC) seepage model documented in ''Drift-Scale THC Seepage Model'' (BSC 2004 [DIRS 169856]). The selection has been conducted in accordance with ''Technical Work Plan for: Near-Field Environment and Transport: Coupled Processes (Mountain-Scale TH/THC/THM, Drift-Scale THC Seepage, and Post-Processing Analysis for THC Seepage) Report Integration'' (BSC 2004 [DIRS 171334]). This technical work plan (TWP) was prepared in accordance with AP-2.27Q, ''Planning for Science Activities''. Section 1.2.3 of the TWP describes planning information pertaining to the technical scope, content, and management of this report. The post-processing analysis for THC seepage (THC-PPA) documented in this report provides a methodology for evaluating the near-field compositions of water and gas around a typical waste emplacement drift as these relate to the chemistry of seepage, if any, into the drift. The THC-PPA inherits the conceptual basis of the THC seepage model, but is an independently developed process. The relationship between the post-processing analysis and other closely related models, together with their main functions in providing seepage chemistry information for the Total System Performance Assessment for the License Application (TSPA-LA), are illustrated in Figure 1-1. The …
Date:
September 29, 2004
Creator:
SUN, Y.
Object Type:
Report
System:
The UNT Digital Library
Stamford American (Stamford, Tex.), Vol. 83, No. 43, Ed. 1 Thursday, January 29, 2004
Weekly newspaper from Stamford, Texas that includes local, state, and national news along with advertising.
Date:
January 29, 2004
Creator:
unknown
Object Type:
Newspaper
System:
The Portal to Texas History
Perry Daily Journal (Perry, Okla.), Vol. 111, No. 19, Ed. 1 Thursday, January 29, 2004
Daily newspaper from Perry, Oklahoma that includes local, state, and national news along with advertising.
Date:
January 29, 2004
Creator:
Brown, Gloria
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Archer County News (Archer City, Tex.), No. 18, Ed. 1 Thursday, April 29, 2004
Weekly newspaper from Archer City, Texas that includes local, state, and national news along with advertising.
Date:
April 29, 2004
Creator:
Lewis, Shelley
Object Type:
Newspaper
System:
The Portal to Texas History
The Baytown Sun (Baytown, Tex.), Vol. 83, No. 300, Ed. 1 Wednesday, September 29, 2004
Daily newspaper from Baytown, Texas that includes local, state, and national news along with advertising.
Date:
September 29, 2004
Creator:
Cash, Wanda Garner
Object Type:
Newspaper
System:
The Portal to Texas History
The Sealy News (Sealy, Tex.), Vol. 117, No. 87, Ed. 1 Friday, October 29, 2004
Semiweekly newspaper from Sealy, Texas that includes local, state, and national news along with advertising.
Date:
October 29, 2004
Creator:
Griffin, Joanie & Horecka, Bobby
Object Type:
Newspaper
System:
The Portal to Texas History
Polk County Enterprise (Livingston, Tex.), Vol. 122, No. 18, Ed. 1 Sunday, February 29, 2004
Semi-weekly newspaper from Livingston, Texas that includes local, state and national news along with advertising.
Date:
February 29, 2004
Creator:
White, Barbara
Object Type:
Newspaper
System:
The Portal to Texas History
The Archer Advocate (Holliday, Tex.), Vol. 2, No. 39, Ed. 1 Wednesday, December 29, 2004
Weekly newspaper from Holliday, Texas that includes local, state, and national news along with advertising.
Date:
December 29, 2004
Creator:
Thomas, John
Object Type:
Newspaper
System:
The Portal to Texas History
The Albany News (Albany, Tex.), Vol. 128, No. 34, Ed. 1 Thursday, January 29, 2004
Weekly newspaper from Albany, Texas that includes local, county, and state news along with extensive advertising.
Date:
January 29, 2004
Creator:
Lucas, Melinda L.
Object Type:
Newspaper
System:
The Portal to Texas History