Here we describe a simple micromolding method to construct three-dimensional arrays of organotypic epithelial tissue structures that approximate in vivo histology. An elastomeric stamp containing an array of posts of defined geometry and spacing is used to mold microscale cavities into the surface of type I collagen gels. Epithelial cells are seeded into the cavities and covered with a second layer of collagen. The cells reorganize into hollow tissues corresponding to the geometry of the cavities. Patterned tissue arrays can be produced in 3-4 h and will undergo morphogenesis over the following one to three days. The protocol can easily be adapted to study a variety of tissues and aspects of normal and neoplastic development.

This report seeks to shed light on whether Senate processing of lower court nominations, particularly to the courts of appeals, has tended over recent decades to slow down in presidential election years. The report begins by reviewing recent debate, and historical events dating back to 1980, concerning whether the Senate and its Judiciary Committee customarily observe a practice referred to as the "Thurmond rule." Next, the report provides narratives on each presidential election year from 1980 to 2004, reviewing Senate and committee actions taken on court of appeals and district court nominations in each of the years. The report then compares these years quantitatively, examining the number and percent of nominations processed and the last dates of committee and Senate action taken.

Laboratory testing was performed to develop a comprehensive understanding of the corrosivity of the tank wastes stored in Double-Shell Tanks using simulants primarily from Tanks 241-AP-105, 241-SY-103 and 241-AW-105. Additional tests were conducted using simulants of the waste stored in 241-AZ-102, 241-SY-101, 241-AN-107, and 241-AY-101. This test program placed particular emphasis on defining the range of tank waste chemistries that do not induce the onset of localized forms of corrosion, particularly pitting and stress corrosion cracking. This document summarizes the key findings of the research program.