‘...and one of time.' is a reinterpretation of a small musical moment from Philip Glass' opera, Einstein on the Beach, centered around the phrase "Berne, Switzerland 1905." This reinterpretation is realized through the use of several different compositional techniques including spectral composition, micropolyphony and dodecaphony, as well as the application of extra-musical models developed by Alan Lightman, John Gardner, Italo Calvino and Albert Einstein.

Changes in spontaneous spike activities recorded from murine frontal cortex networks grown on substrate-integrated microelectrodes were used to determine the dissociation constant (KB) of three GABAA antagonists. Neuronal networks were treated with fixed concentrations of GABAA antagonists and titrated with muscimol, a GABAA receptor agonist. Muscimol decreased spike activity in a concentration dependent manner with full efficacy (100% spike inhibition) and a 50% inhibitory concentration (IC50) of 0.14 ± 0.05 µM (mean ± SD, n=6). At 10, 20, 40 and 80 µM bicuculline, the muscimol IC50 values were shifted to 4.3 ± 1.8 µM (n=6), 6.8 ± 1.7 µM (n=6), 19.3 ± 3.54 µM (n=10) and 43.5 µM (n=2), respectively (mean ± SD). Muscimol titration in the presence of 10, 20, 40 µM of gabazine resulted in IC50s values of 20.1 (n=2), 37.17 (n=4), and 120.45 (n=2), respectively. In the presence of 20, 80, and 160 µM of TMPP (trimethylolpropane phosphate) the IC50s were 0.86 (n=2), 3.07 (n=3), 6.67 (n=2) µM, respectively. Increasing concentrations of GABAA antagonists shifted agonist log concentration-response curves to the right with identical efficacies, indicating direct competition for the GABAA receptor. A Schild plot analysis with linear regression resulted in slopes of 1.18 ± 0.18, 1.29 …

A novel scheme of optimizing the individual components of a phase locked loop (PLL) which is used for stable clock generation and synchronization of signals is considered in this work. Verilog-A is used for the high level system design of the main components of the PLL, followed by the individual component wise optimization. The design of experiments (DOE) approach to optimize the analog, 45nm voltage controlled oscillator (VCO) is presented. Also a mixed signal analysis using the analog and digital Verilog behavior of components is studied. Overall a high level system design of a PLL, a systematic optimization of each of its components, and an analog and mixed signal behavioral design approach have been implemented using cadence custom IC design tools.

Following Ajzen/Fishbein's 1980 Theory of Reasoned Action, influences of hospitality students' external variables (age, gender, university classification, and work experience) on computer attitudes, and relationships between computer attitudes and intentions to learn and use computers were tested. A sample of 412 hospitality students completed two measurements: Loyd/Gressard's 1984 Computer Attitude Scale, and Behavioral Intentions to Learn and Use Computers. Males and females had positive computer attitudes. Graduates had more positive computer attitudes. No interaction effect existed between gender and classification. No relationships existed between age and work experience on computer attitudes. Computer attitudes positively correlated with intentions to learn and use computers. Results supported the Theory of Reasoned Action. External variables partially influence attitudes and attitudes influence intentions.