Accurate assessment of sleep-wake patterns is important for sleep researchers and clinicians. Actigraphs are low-cost, non-intrusive, wrist-worn activity detectors used to estimate sleep-wake patterns in a natural environment for several nights. Although actigraphy shows good sensitivity (sleep detection), it has consistently demonstrated poor specificity (wakefulness detection while lying in bed relatively motionless). Because insomnia is characterized by wakefulness in bed, actigraphy may not be a valid objective measure of wakefulness for this group. It is possible that refinement of actigraphy software settings for sleep/wake algorithms might improve specificity. The current studies investigated this hypothesis by comparing wake parameters from 48 combinations of actigraphy settings to determine which sleep/wake algorithms best inform insomnia diagnosis and treatment. In the first study, none of the 48 actigraphy setting combinations consistently discriminated between adults with insomnia (n = 69) and non-insomnia (n = 80) on all three wake parameters, and no setting clearly discriminated between groups for the composite variable, total wake time. Similarly, in the second study, no setting combinations consistently discriminated between adults treated for insomnia (n = 18) and controls with untreated insomnia (n = 26) on all three wake parameters. Although two setting combinations discriminated between groups for the composite …

Marijuana is the second most commonly used substance in the US. A growing literature suggests that socially anxious individuals use marijuana to manage their symptoms in social situations, which may explain why they are also more likely to experience problems. Unfortunately, the majority of the literature is based on research conducted with adult samples or the co-occurrence of diagnoses in adolescent samples. The proposed study sought to test the link between social anxiety (SA) and proxies for ‘real-time' marijuana use behaviors (i.e., use willingness) as well as use-related problems among adolescents. Participants were 69 adolescents (15-17; 55% female) recruited from the community reporting any lifetime marijuana use. Participants were randomly assigned to a novel social rejection or neutral laboratory task and completed measures of SA, marijuana use frequency, and related problems. Consistent with adult findings, main effects of SA and experimental condition on marijuana use willingness were expected to be qualified by an interaction in which the greatest marijuana use willingness would occur among high SA youth post-rejection (H1), SA would be positively related to marijuana use problems (H2), and among adolescents in the rejection condition, marijuana use willingness would be positively correlated with use problems (H3). Only H2 was …

If mania and depression are part of the same pathological processes, one would predict that episodes of one prospectively increase the odds of episodes of the other. The aim of the present study was to test this hypothesis. For comparison purposes, their relationship was contrasted to the relationship between mania and periods of psychosis. Exploratory analyses also tested the degree to which episodes of each occur with greater frequency over time (i.e., kindling). Participants for the present study came from the Suffolk County Mental Health Project (N = 628), a study of first-admission patients with psychosis. Of these participants, 144 met diagnostic criteria for bipolar I disorder and were analyzed for the current study. Results indicated that mania in a given month predicted depression the following month, even after controlling for other symptoms. The reverse, however, was not the case. Mania and psychosis, in contrast, were found to be robust predictors of one another from month to month. Effects were not due to treatment or demographic differences. These findings provide evidence that mania and depression are weakly related. In contrast, mania and psychosis are more closely linked. Findings are consistent with suggestions that psychiatric nosology regroup mania more closely with …