Prokaryotic life on earth is manifested by its diversity and omnipresence. These microbes serve as natural sources of a large variety of compounds with the potential to serve the ever growing, medicinal, chemical and transportation needs of the human population. However, commercially viable production of these compounds can be realized only through significant improvement of the native production capacity of natural isolates. The most favorable way to achieve this goal is through the genetic manipulation of metabolic pathways that direct the production of these molecules. While random mutagenesis and screening have dominated the industrial production of such compounds in the past our increased understanding of microbial physiology over the last five decades has shifted this trend towards rational approaches for metabolic design. Major drivers of this trend include recombinant DNA technology, high throughput characterization of macromolecular cellular components, quantitative modeling for metabolic engine ring, targeted combinatorial engineering and synthetic biology. In this chapter we track the evolution of microbial engineering technologies from the black box era of random mutagenesis to the science and engineering-driven era of metabolic design.

Interview with Dr. James F. White, minister at the Perkins School of Theology and leader of the Citizens Organization for a Sound Trinity (COST) group, which was in opposition to the Trinity Barge Canal construction project. White provides details about newspaper coverage of the issue, the group's involvement in politics, and his views of other political issues.

Scrapbook filled primarily with flyers, programs, letters, newspaper clippings, and other ephemera from Mabel Malone's college days. Photos of friends and family members can be seen on a few pages near the back of the book.

"The Street and Avenue Guide consists of two sections. The first section comprises the numbered streets in numerical order. The second section comprises the streets by name in alphabetical order."

Proposed budget for the University of Texas at Austin outlining projected income and expenditures, with supporting documentation.

Proposed budget for the University of Texas at Austin outlining projected income and expenditures, with supporting documentation.

Annual catalog for John Tarleton Agricultural College describing the school, admission requirements, tuition, financial aid, departments, and classes for the 1921 - 1922 school year, with announcements for 1922 - 1923.

Volume provides a summary of the progress of each agricultural experiment station. Also includes statistics, discussions of foreign investigations, and selected studies.