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Biosignatures of Pathogen and Host (open access)

Biosignatures of Pathogen and Host

In information theory, a signature is characterized by the information content as well as noise statistics of the communication channel. Biosignatures have analogous properties. A biosignature can be associated with a particular attribute of a pathogen or a host. However, the signature may be lost in backgrounds of similar or even identical signals from other sources. In this paper, we highlight statistical and signal processing challenges associated with identifying good biosignatures for pathogens in host and other environments. In some cases it may be possible to identify useful signatures of pathogens through indirect but amplified signals from the host. Discovery of these signatures requires new approaches to modeling and data interpretation. For environmental biosignal collections, it is possible to use signal processing techniques from other applications (e.g., synthetic aperture radar) to track the natural progression of microbes over large areas. We also present a computer-assisted approach to identify unique nucleic-acid based microbial signatures. Finally, an understanding of host-pathogen interactions will result in better detectors as well as opportunities in vaccines and therapeutics.
Date: August 27, 2002
Creator: Fitch, J. P.; Chromy, B. A.; Forde, C. E.; Garcia, E.; Gardner, S. N.; Gu, P. P. et al.
Object Type: Article
System: The UNT Digital Library
The Clifton Record (Clifton, Tex.), Vol. 107, No. 104, Ed. 1 Friday, December 27, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 104, Ed. 1 Friday, December 27, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: December 27, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
Extensional wave attenuation and velocity in partially-saturated sand in the sonic frequency range (open access)

Extensional wave attenuation and velocity in partially-saturated sand in the sonic frequency range

Extensional wave attenuation and velocity measurements on a high permeability Monterey sand were performed over a range of gas saturations for imbibition and degassing conditions. These measurements were conducted using extensional wave pulse propagation and resonance over a 1 - 9 kHz frequency range for a hydrostatic confining pressure of 8.3 MPa. Analysis of the extensional wave data and the corresponding X-ray CT images of the gas saturation show strong attenuation resulting from the presence of the gas (QE dropped from 300 for the dry sand to 30 for the partially-saturated sand), with larger attenuation at a given saturation resulting from heterogeneous gas distributions. The extensional wave velocities are in agreement with Gassmann theory for the test with near-homogeneous gas saturation and with a patchy saturation model for the test with heterogeneous gas saturation. These results show that partially-saturated sands under moderate confining pressure can produce strong intrinsic attenuation for extensional waves.
Date: June 17, 2002
Creator: Liu, Z.; Rector, J. W.; Nihei, K. T.; Tomutsa, L.; Myer, L. R. & Nakagawa, S.
Object Type: Article
System: The UNT Digital Library
The Clifton Record (Clifton, Tex.), Vol. 107, No. 102, Ed. 1 Friday, December 20, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 102, Ed. 1 Friday, December 20, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: December 20, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 62, Ed. 1 Friday, August 2, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 62, Ed. 1 Friday, August 2, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: August 2, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
Ecotoxicological Investigations in Effluent-Dominated Stream Mesocosms (open access)

Ecotoxicological Investigations in Effluent-Dominated Stream Mesocosms

The University of North Texas Stream Research Facility (UNTSRF) was designed to examine contaminant impacts on effluent-dominated stream ecosystems. Stream mesocosms, fed municipal effluent from the City of Denton, TX, Pecan Creek Water Reclamation Plant (PCWRP), were treated with 0, 15 or 140 µg/L cadmium for a 10-day study in August 2000. Laboratory toxicity test and stream macroinvertebrate responses indicated that cadmium bioavailability was reduced by constituents of effluent-dominated streams. The Biotic Ligand Model (BLM) for Cd was used to predict a 48 hour Cd EC50 for Ceriodaphnia dubia of 280 µg/L in these effluent-dominated streams. This value is higher that an EC50 of 38.3 µg/L Cd and a 7-day reproduction effect level of 3.3 µg/L Cd generated for C. dubia in reconstituted laboratory hard water. These results support use of a cadmium BLM for establishing site-specific acute water quality criteria in effluent-dominated streams. Although not affected by 15 µg/L treatments, organisms accumulated Cd in 15 µg/L treated streams. Hence, over longer exposure periods, Cd accumulation may increase and a no effect level may be lower than the observed 10-day no effect level of 15 µg/L. A toxicity identification evaluation procedure was utilized with in vitro and in vivo bioassays …
Date: December 2002
Creator: Brooks, Bryan W.
Object Type: Thesis or Dissertation
System: The UNT Digital Library
The Clifton Record (Clifton, Tex.), Vol. 107, No. 29, Ed. 1 Wednesday, April 10, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 29, Ed. 1 Wednesday, April 10, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: April 10, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 95, Ed. 1 Wednesday, November 27, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 95, Ed. 1 Wednesday, November 27, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: November 27, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 66, Ed. 1 Friday, August 16, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 66, Ed. 1 Friday, August 16, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: August 16, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 88, Ed. 1 Friday, November 1, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 88, Ed. 1 Friday, November 1, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: November 1, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
Polarization for Background Reduction in EDXRF - The Technique That Would Not Work (open access)

Polarization for Background Reduction in EDXRF - The Technique That Would Not Work

As with all electromagnet radiation, polarization of x-rays is a general phenomenon. Such polarization has been known since the classic experiments of Barkla in 1906. The general implementation of polarization to x-ray analysis had to await the fixed geometry of energy-dispersive systems. The means of optimizing these systems is shown in this review paper. Improved detection limits are the result.
Date: July 24, 2002
Creator: Ryon, R W
Object Type: Article
System: The UNT Digital Library
The Clifton Record (Clifton, Tex.), Vol. 107, No. 35, Ed. 1 Wednesday, May 1, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 35, Ed. 1 Wednesday, May 1, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: May 1, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 100, Ed. 1 Friday, December 13, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 100, Ed. 1 Friday, December 13, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: December 13, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
FAILPROB--A Computer Program to Compute the Probability of Failure of a Brittle Component (open access)

FAILPROB--A Computer Program to Compute the Probability of Failure of a Brittle Component

FAILPROB is a computer program that applies the Weibull statistics characteristic of brittle failure of a material along with the stress field resulting from a finite element analysis to determine the probability of failure of a component. FAILPROB uses the statistical techniques for fast fracture prediction (but not the coding) from the N.A.S.A. - CARES/life ceramic reliability package. FAILPROB provides the analyst at Sandia with a more convenient tool than CARES/life because it is designed to behave in the tradition of structural analysis post-processing software such as ALGEBRA, in which the standard finite element database format EXODUS II is both read and written. This maintains compatibility with the entire SEACAS suite of post-processing software. A new technique to deal with the high local stresses computed for structures with singularities such as glass-to-metal seals and ceramic-to-metal braze joints is proposed and implemented. This technique provides failure probability computation that is insensitive to the finite element mesh employed in the underlying stress analysis. Included in this report are a brief discussion of the computational algorithms employed, user instructions, and example problems that both demonstrate the operation of FAILPROB and provide a starting point for verification and validation.
Date: February 1, 2002
Creator: WELLMAN, GERALD W.
Object Type: Report
System: The UNT Digital Library
The Clifton Record (Clifton, Tex.), Vol. 107, No. 83, Ed. 1 Wednesday, October 16, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 83, Ed. 1 Wednesday, October 16, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: October 16, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 84, Ed. 1 Friday, October 18, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 84, Ed. 1 Friday, October 18, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: October 18, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 97, Ed. 1 Wednesday, December 4, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 97, Ed. 1 Wednesday, December 4, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: December 4, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 36, Ed. 1 Friday, May 3, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 36, Ed. 1 Friday, May 3, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: May 3, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 87, Ed. 1 Wednesday, October 30, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 87, Ed. 1 Wednesday, October 30, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: October 30, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 8, Ed. 1 Friday, January 25, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 8, Ed. 1 Friday, January 25, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: January 25, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 54, Ed. 1 Friday, July 5, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 54, Ed. 1 Friday, July 5, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: July 5, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 72, Ed. 1 Friday, September 6, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 72, Ed. 1 Friday, September 6, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: September 6, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 40, Ed. 1 Friday, May 17, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 40, Ed. 1 Friday, May 17, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: May 17, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History
The Clifton Record (Clifton, Tex.), Vol. 107, No. 7, Ed. 1 Wednesday, January 23, 2002 (open access)

The Clifton Record (Clifton, Tex.), Vol. 107, No. 7, Ed. 1 Wednesday, January 23, 2002

Semi-weekly newspaper from Clifton, Texas that includes local, state, and national news along with advertising.
Date: January 23, 2002
Creator: Smith, W. Leon
Object Type: Newspaper
System: The Portal to Texas History